Results 141 to 150 of about 1,231,622 (330)

Cell signaling and regulation of CFTR expression in cystic fibrosis cells in the era of high efficiency modulator therapy [PDF]

, 2023
Alessandra Ghigo, Chiara De Santi, Merrill Hart, Nilay Mitash, Agnieszka Swiatecka‐Urban   +4 more
openalex   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, EarlyView.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

Effect of Cystic Fibrosis Transmembrane Conductance Regulator Modulators on Liver Enzymes Among Patients With Cystic Fibrosis: A Systematic Review and Meta-Analysis

Gastro Hep Advances
Backgrounds and Aims: This paper seeks to use existing literature to investigate the use of Cystic Fibrosis Transmembrane Conductance (CFTR) modulators and their safety and effects on the liver enzymes of cystic fibrosis (CF) patients with and without ...
Tahne Vongsavath, Kyaw Min Tun, Dwaipayan Mukhopadhyay, Chun-Han Lo, Ashok Singh, Rajan Amin, Patrick Twohig, Sammy Saab, Vignan Manne   +8 more
doaj   +1 more source

Experience to date with CFTR modulators during pregnancy and breastfeeding in the British Columbia Cystic Fibrosis clinic

, 2022
Jodi Goodwin, Bradley S. Quon, Pearce Wilcox   +2 more
openalex   +1 more source

Characterizing CFTR modulated sweat chloride response across the cf population: Initial results from the CHEC-SC study [PDF]

, 2022
Nicole Mayer-Hamblett, Edith T. Zemanick, Katherine Odem‐Davis, Donald R. VanDevanter, Mark N. Warden, Steven M. Rowe, J. Young, MW Konstan, for-the-CHEC-SC-Study-Group   +8 more
openalex   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Bronchiectasis:a case-based approach to investigation and management [PDF]

, 2018
Bronchiectasis is a chronic respiratory disease characterised by a syndrome of productive cough and recurrent respiratory infections due to permanent dilatation of the bronchi.
Agarwal, Agarwal, Bonaiti, Cartier, Chu, Cole, Erasmus, Farrell, Greenberger, Gremmo, Hosie, James D. Chalmers, Martina Contarini, Mirsaeidi, Neeld, Nicolini, Shapiro, Simon Finch   +17 more
core   +3 more sources

EPS8.05 One-minute sit-to-stand test improves with CFTR modulators [PDF]

, 2023
M. Penelle, Anne-Sophie Aubriot, C. R. Gonçalves, Christophe Goubau, Silvia Berardis, Grégory Reychler, Sophie Gohy   +6 more
openalex   +1 more source

Modulator-refractory cystic fibrosis: Defining the scope and challenges of an emerging at-risk population

Therapeutic Advances in Respiratory Disease
Cystic fibrosis (CF) causes life-shortening respiratory and systemic disease due to dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel.
Lindsay Somerville, Larry Borish, Imre Noth, Dana Albon   +3 more
doaj   +1 more source

Identification of Novel Genes Selectively Expressed in the Follicle-Associated Epithelium from the Meta-Analysis of Transcriptomics Data from Multiple Mouse Cell and Tissue Populations [PDF]

, 2012
The follicle-associated epithelium (FAE) overlying the Peyer’s patches and the microfold cells (M cells) within it are important sites of antigen transcytosis across the intestinal epithelium.
A. Kobayashi, Aziz, Bevilacqua, Bradford, D'Angelo, D. S. Donaldson, Frith, Frith, H. Ohno, Hanayama, Hase, Hase, Hase, He, Hopkins, I. R. Williams, J. K. Baillie, Kanaya, Kawano, Kong, Kujala, Lange, Mabbott, Montenegro, N. A. Mabbott, Park, S. Fukuda, Steinbrecher, T. C. Freeman, T. Kanaya, Terahara, Terahara, The FANTOM Consortium, Ueki, van der Flier, Verbrugghe, Wang, Wang, Wong   +38 more
core   +1 more source