Results 151 to 160 of about 42,079 (241)

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida   +7 more
wiley   +1 more source

Triphenylphosphonium is an effective targeting moiety for plant mitochondria. [PDF]

open access: yesNew Phytol
Lazary S   +8 more
europepmc   +1 more source

Intramuscular neutrophil‐derived immunometabolic niches locally boost insulin‐responsive GLUT4 translocation after muscle contraction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Contraction‐induced formation of a NET‐based immunometabolic niche potentiates regional insulin sensitivity and GLUT4 translocation. The schematic model illustrating how skeletal muscle contraction promotes a NET‐based immunometabolic niche that enhances regional insulin sensitivity.
Weijian Chen, Makoto Kanzaki
wiley   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

open access: yesInternational Journal of Cancer, Volume 158, Issue 10, Page 2641-2649, 15 May 2026.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange   +9 more
wiley   +1 more source

Post‐surgery level of circulating DNA in stage III colon cancer patients: Impact on the reliability of minimal residual disease detection

open access: yesInternational Journal of Cancer, Volume 158, Issue 10, Page 2771-2783, 15 May 2026.
What's New? Circulating nuclear DNA (cir‐nDNA)‐based assessment of minimal residual disease (MRD) offers powerful post‐surgery prognostic insight for stage III colon cancer (CC). Sparse knowledge of post‐surgical variations and origins in cir‐nDNA, however, has limited its clinical application.
Andrei Kudriavtsev   +17 more
wiley   +1 more source

Inflammatory Mediators Both Directly and Indirectly Promote Microglial Proliferation

open access: yesGlia, Volume 74, Issue 5, May 2026.
– CSF2, IL3, and TNFɑ directly promote microglial proliferation. – Neuron‐secreted factors suppress microglial proliferation. – IL1 cytokines promote CSF2 release from astrocytes, which promotes microglial proliferation. ABSTRACT Microglia—the predominant immune cell of the central nervous system (CNS)—possess an astounding capacity for proliferation ...
Brady P. Hammond   +4 more
wiley   +1 more source

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