Results 171 to 180 of about 80,761 (294)

The “Tianyu” Formulation Alleviates Rheumatoid Arthritis by Modulating the NLRP3/Caspase‐1/GSDMD‐Mediated Pyroptosis Pathway

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Proposed signaling pathway by which TY modulates NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis. ABSTRACT This research focuses on exploring the modulation of pyroptosis and its underlying mechanisms via the “Tianyu” formulation (TY), a traditional Chinese medicine, in human rheumatoid arthritis fibroblast‐like synovial cells (RA‐HFLS) and a collagen ...
Yueya Zhu, Xinying Cai, Qiuhan Zheng, Chunqiu Fang, Zhi Pan, Yinghang Wang   +5 more
wiley   +1 more source

Photodynamic Inactivation Enhances Antibiotic Efficacy Without Affecting Drug Stability: Insights into Photosensitizer-Antibiotic Combination Therapies. [PDF]

Int J Mol Sci
Acosta RB, Durantini EN, Spesia MB.
europepmc   +1 more source

Characterizing the Impact of Nucleoid‐Associated Proteins on HU‐DNA Interactions by Live‐Cell Single‐Molecule Tracking

ChemPhysChem, Volume 27, Issue 9, 14 May 2026.
The nucleoid‐associated proteins Dps, H‐NS, and HU shape the bacterial chromosome in the deep stationary phase through their interactions with the nucleoid.The bacterial nucleoid undergoes extensive structural reorganization during growth, influenced by nucleoid‐associated proteins (NAPs) whose interactions and effects on nucleoid organization remain ...
D. E. H. Fuller, X. Dai, L. A. McCarthy, L. E. Way, X. Wang, J. S. Biteen   +5 more
wiley   +1 more source

Green removal and waste valorization of ciprofloxacin from water using zinc-iron LDH-chia seed biocomposites: integrated adsorption, computational modeling, and electrochemical conversion. [PDF]

RSC Adv
Mahgoub SM, Rudayni HA, Allam AA, Alsalamah SA, Elrafey A, Abdelazeem R, Kotp AA, Abdelsatar MM, Shafi R, Mahmoud R.   +9 more
europepmc   +1 more source

Disrupted CO Migration and Reversed Activity in CuAg Spatiotemporal Tandem Catalysts for C2+ Production

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
Rational catalyst architecture is essential for driving the electrochemical CO2 reduction toward multi‐carbon (C2+) products; however, many previously reported strategies rely on intricate structural designs that hinder large‐scale implementation.
Lei Wang, Yimin A. Wu
wiley   +1 more source

Anticancer Effect of the Triphenylphosphonium-Conjugated Quinolone Antibiotics Targeting Mitochondrial DNA Replication. [PDF]

Cancer Sci
Qiao Y, Kida Y, Lai X, Koshikawa N, Igarashi R, Takatori A, Takenaga K.   +6 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, Volume 16, Issue 5, Page 932-943, May 2026.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Antimicrobial resistance in ESKAPEE pathogens isolated from institutionalized vs. non-institutionalized elderly patients with urinary tract infections: a 5-years study. [PDF]

World J Urol
Ramírez-Vilariño G, Alonso-González I, Lopez-Picado A, Burgos-Alonso N.   +3 more
europepmc   +1 more source

Safe and Localized Lentiviral Gene Delivery via Injectable Mesoporous Scaffolds for Potent Antitumor Immunity

Advanced Materials, Volume 38, Issue 25, 4 May 2026.
This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen, Yeon‐ju Kim, Jihye Im, Dong Kwang Min, Hyunsu Shin, Thuy An Trinh, Ngoc Man Phan, Min‐jeong Son, Ji‐yeon Shim, Ye‐lim Lee, Yujeong Ha, Kwang‐il Lim, Jaeyun Kim   +12 more
wiley   +1 more source

Ciprofloxacin enhances RSL3-induced ferroptosis by promoting mitochondrial Zn²⁺ accumulation via the STING1-CAV2 pathway. [PDF]

J Biol Chem
Tang H, Chen F, Cai X, Lin J, Xiang L, Kang R, Zhang Z, Tang D, Liu J.   +8 more
europepmc   +1 more source