Results 181 to 190 of about 80,761 (294)

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

A review of pharmaceutical removal from wastewater via hydrodynamic cavitation. [PDF]

Ultrason Sonochem
Liu P, Gaudino EC, Lee J, Cravotto G.
europepmc   +1 more source

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

Fluorescence-Based Absent Allele-Specific Amplification (FAASA) for High-Throughput Detection of Absent Alleles. [PDF]

Bio Protoc
Running KLD, Seneviratne S, Zhang Z, Singh G, Fiedler JD, Faris JD.   +5 more
europepmc   +1 more source

Abi3S212F Alzheimer's disease variant alters plaque structure and disrupts microglia

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract BACKGROUND Genetic variants affecting microglial function can influence Alzheimer's disease (AD) risk, yet the underlying mechanisms remain unclear. The AD‐associated ABI3S209F (Abi3S212F in mouse) variant regulates cytoskeletal dynamics, but its in vivo impact on pathology is unknown. METHODS: An Abi3S212F mouse was developed and crossed with
Claire A. Butler, Min Sung Gee, Katie O'Gara, Giedre Milinkeviciute, Celia Da Cunha, Shimako Kawauchi, Yueh‐Hao Lu, Nellie Kwang, Kate I. Tsourmas, Christiana Prekopa, Zechuan Shi, Heidi Yahan Liang, Sherilyn D. Collins, Zachary A. Pashkutz, Jenna A. Sanchez, Kai‐Xuan Shi, Amber D. Walker, Shuling Wang, Maigan L. A. Wong, Karina Genaro, Jonathan Neumann, Angela Gomez‐Arboledas, Duc M. Duong, Nicholas T. Seyfried, Andrea J. Tenner, Frank M. LaFerla, Ali Mortazavi, Vivek Swarup, Grant R. MacGregor, Kim N. Green   +29 more
wiley   +1 more source

Phenotypic and genotypic characterization of multidrug-resistant avian pathogenic <i>Escherichia coli</i> across life stages of captive African Houbara bustards: Conservation and One Health implications. [PDF]

Vet World
Rashad SM.
europepmc   +1 more source

Immortalization of Human Adult Alveolar Epithelial Cells to Study Environmental Exposures of the Distal Lung

Current Protocols, Volume 6, Issue 5, May 2026.
Abstract Alveolar epithelial cell type 1 (AT1) and type 2 (AT2) cells make up the saccular gas exchange units of the lung, called alveoli. Formation of alveoli during lung development accounts for the expansive surface area of the lung, allowing for proper respiration and delivery of oxygen to the body.
Evelyn Tran, Laurence St. Pierre, Diego Velarde, Bianca dal Bó, Juan Ramon Alvarez, Kweku Ofosu‐Asante, Nazarius S. Lamango, Yong Huang, Crystal N. Marconett, Zea Borok, Beiyun Zhou, Ite A. Offringa   +11 more
wiley   +1 more source

Drug delivery system based on an antibacterial layer-by-layer coating on urinary catheters: an experimental and simulation approach. [PDF]

Front Bioeng Biotechnol
Pulido R, Naveas N, Fernández-Alonso FJ, Manso-Silván M, Soriano L, Torres-Ulloa C, Mena-Ulecia K, Recio-Sánchez G, Garcia-Sandoval JP, Hernández-Montelongo J.   +9 more
europepmc   +1 more source

Salt in the Wound: Assessing Pathogen Susceptibility in Amphibian Populations Across a Gradient of Salt Pollution

Ecology and Evolution, Volume 16, Issue 5, May 2026.
The survival function of nine larval wood frog populations and their viral loads when exposed to FV3. The populations were collected as eggs from a range of salt‐polluted ponds. Viral load data are means ±1 SE. The populations are ordered in terms of the saltiness of their natal ponds.
Rick A. Relyea, Jason T. Hoverman, Jessica Hua, Devin K. Jones, Melissa Lech, Brian Mattes, Candace Schermerhorn, Bryon Tuthill, Isabela Tuthill   +8 more
wiley   +1 more source

Comparative analysis of drug susceptibility among different Mycobacterium abscessus morphotypes. [PDF]

BMC Microbiol
Cheng K, Guo J, Shang Y, Ren W, Zhao W, Li S.   +5 more
europepmc   +1 more source