Results 221 to 230 of about 80,761 (294)

Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells

open access: yesFundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.
ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu   +4 more
wiley   +1 more source

Biowaste Composting as a Sustainable Platform for Bacterial CO Production: Evidence From cooS Gene Expression and Microbial Community Profiling

open access: yesGCB Bioenergy, Volume 18, Issue 5, May 2026.
This study demonstrates, for the first time, the expression of the cooS gene during composting, confirming microbial CO production under mesophilic conditions. The results highlight composting as a novel waste‐to‐biochemicals process, offering a sustainable, low‐carbon pathway for generating carbon monoxide via bacterial CO dehydrogenase activity ...
Karolina Sobieraj   +2 more
wiley   +1 more source

The Dual Role of Methyl Caffeate: Growth Inhibition of Pseudomonas syringae and Induction of Resistance to Bacterial Speck Disease in Tomato

open access: yesMolecular Plant Pathology, Volume 27, Issue 5, May 2026.
Methyl caffeate exhibits dual functionality against Pseudomonas syringae pv. tomato. It directly disrupts bacterial membrane integrity, induces reactive oxygen species accumulation, and inhibits flagellar motility and the type III secretion system. Concurrently, it primes plant defence by activating defence‐related gene expression and enzyme activities,
Yarui Yang   +11 more
wiley   +1 more source

Pro‐Vitamin A Biofortified Cavendish Banana: Trait Stability in the Field

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3327-3344, May 2026.
ABSTRACT Vitamin A deficiency (VAD), a major global health concern, has driven efforts to develop staple crops with enhanced pro‐vitamin A (pVA) content. Delivering meaningful nutritional benefits, however, requires technologies that maintain elevated carotenoid levels under field conditions. Previous proof‐of‐concept work demonstrated that pVA content
Jimmy M. Tindamanyire   +7 more
wiley   +1 more source

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