Results 191 to 200 of about 70,973 (282)

Regulated versus unregulated competition: How drug shortages boost illegal pharmacy sales

Strategic Management Journal, Volume 47, Issue 7, Page 1811-1839, July 2026.
Abstract Research Summary This study examines how product shortages among legal firms create competitive opportunities for illegal firms. We analyze 713 drug shortages in the United States between 2017 and 2023 and show that shortages substantially increase illicit pharmacies’ sales of affected drugs, which rise by 40.5% during shortages and remain 32 ...
Luis Diestre, Benjamin Barber IV
wiley   +1 more source

Vericiguat: A New Horizon for Heart Failure Treatment. [PDF]

Rev Cardiovasc Med
Carbonaro C, Bocchino PP, Bertello E, Griffith Brookles C, Angelini F, Gallone G, Pidello S, Feneziani A, Raineri C, De Ferrari GM.   +9 more
europepmc   +1 more source

Crataegus oxyacantha Extract Enhances Cardiac Adaptation and Reduces Oxidative‐Inflammatory Stress in Broiler Chickens Raised at High Altitude Under Cold Stress

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Crataegus oxyacantha extract at 0.4 mL/L improved cardiac function in broilers under cold stress and high altitude by increasing nitric oxide synthase gene expression, boosting nitric oxide, reducing endothelin‐1 gene expression, and lowering oxidative‐inflammatory stress, offering a natural solution to mitigate pulmonary hypertension syndrome ...
Behnam Ahmadipour, Hossein Hassanpour, Samira Abaszadeh, Majid Kalantar   +3 more
wiley   +1 more source

Effects of the novel phosphodiesterase 9 inhibitor irsenontrine on CSF proteomics profile in Aβ⁺ and Aβ^- dementia with Lewy bodies patients. [PDF]

Alzheimers Res Ther
Oosthoek M, In 't Veld SGJG, Vermunt L, Ye Y, van Ingen M, Koel-Simmelink M, Vijverberg EGB, Saxena S, Hersch S, Irizarry M, Sachdev P, Teunissen CE.   +11 more
europepmc   +1 more source

cGMP Signaling in Brown Adipocytes

Obesity is characterized by an imbalance between energy intake and expenditure, resulting in an abnormal accumulation of white adipose tissue (WAT), the primary form of energy storage in humans.
Rowland, Daniel Ray
core  

Increasing the Acceptability of Insect‐Based Foods as Future Foods: A Comprehensive Review of Barriers, Strategies, and Pathways to Mainstream Adoption

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT Edible insects are increasingly recognized for their high nutritional value and favorable environmental profile, yet their acceptance (defined as the continuum from willingness to try and purchase to repeated consumption) in Western and globalized food systems remains limited by cultural, sensory, regulatory, and economic barriers.
Jose Miguel Alvarez Suarez, Andrea M. Liceaga   +1 more
wiley   +1 more source

NO- and S-nitrosothiols-dependent relaxation in large and small resistance blood vessels. [PDF]

Front Physiol
Lillo MA, Beuve A.
europepmc   +1 more source

Drugst.One DREAM—Drug repurposing through expert annotation and modification

British Journal of Pharmacology, Volume 183, Issue 13, Page 3503-3516, July 2026.
Background and Purpose Complex diseases often lack an actionable understanding of their underlying causal biological mechanisms, which leads to treating symptoms rather than causes. Network and systems medicine define disease mechanisms through disease‐associated genes, their encoded proteins and their protein–protein interactions (PPIs), thus forming ...
Lisa M. Spindler, Johannes Kersting, Quirin Manz, Michael Hartung, Andreas Maier, Zeinab M. Mamdouh, Ana I. Casas, Jan Baumbach, Markus List   +8 more
wiley   +1 more source

Phosphodiesterase 9 (PDE9) Inhibitors May Provide Effective Treatments for Neurodegenerative, Cardiovascular and Other Diseases. [PDF]

ACS Med Chem Lett
Abdel-Magid AF.
europepmc   +1 more source

Circadian‐Related Serotonin/Melatonin Level Modulates Cisplatin Ototoxicity Susceptibility Depended on NOS3–NO Pathway

Journal of Pineal Research, Volume 78, Issue 4, July 2026.
ABSTRACT Hearing impairment is attributed to factors such as age, genetic predisposition, and environmental influences, among which environmental factors are considered modifiable. Among various environmental factors, the role of poor lifestyle habits is particularly critical, yet the specific mechanisms by which they contribute to hearing damage ...
Siyu Qiu, Shiyi Cai, Rong Xie, Chang Liu, Yingzi He   +4 more
wiley   +1 more source