Results 191 to 200 of about 56,515 (255)

β3‐AR/β‐arrestin2 Interaction Triggers Cardiac Fibrosis Through JNK/c‐Jun Pathway in Cardiac Fibroblasts

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Myocardial fibrosis (MF) is a critical pathological substrate of heart failure (HF), and β3‐adrenergic receptor (β3‐AR) has been implicated in cardiac remodelling with controversial roles. This study aimed to clarify the pro‐fibrotic mechanism of β3‐AR in cardiac fibroblasts and its association with β‐arrestin2‐mediated biased activation ...
Zhongcheng Xu, Min Zhu, Chun Zhou, Juncang Duan, Jian Ding, Jun Liu, Xuan Ying, Jie Wu, Yang Dong, Wenbiao Wang, Zhaohui Qiu   +10 more
wiley   +1 more source

Characterization of a New PRKG1 Mutation Associated With Thoracic Aortic Aneurysm and Dissection. [PDF]

JACC Basic Transl Sci
Casteel DE.
europepmc   +1 more source

Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance

New Phytologist, Volume 251, Issue 3, Page 975-995, August 2026.
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap, Arash Fazeli, Ali Bandehagh, Nicolas L. Taylor   +3 more
wiley   +1 more source

Nutritional and Therapeutic Strategies in Paediatric Phenylketonuria: A Narrative Literature Review. [PDF]

Nutrients
Jones H, Strehle EM.
europepmc   +1 more source

Phosphodiesterase inhibitors as emerging therapeutics for skeletal disorders: A comprehensive review of mechanisms and repurposing potential. [PDF]

Bone Rep
Ursachi VC, Horak J, Fafilek B.
europepmc   +1 more source

Brain sparing in fetal growth restriction: The double‐edged sword of fetal hypoxaemia

The Journal of Physiology, Volume 604, Issue 15, Page 6259-6280, 1 August 2026.
Abstract figure legend The double‐edged sword of brain sparing. Fetal hypoxaemia triggers a coordinated adaptive response characterised by redistribution of cardiac output toward essential organs, including the brain, and a reduction in overall metabolic activity to preserve oxygen supply.
Beth J. Allison, Tegan A. White, Emily J. Camm, Suzanne L. Miller   +3 more
wiley   +1 more source

Xingpi Yanger Granule combined with conventional medication for the treatment of nocturnal enuresis: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Front Pediatr
Zhao RP, Sun T, Zhang QW, Guo MY, Li SS, Zheng H.   +5 more
europepmc   +1 more source

Beta‐casein in human milk is associated with infant stool frequency: A pilot proteomics study

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Breast milk proteins may regulate gut function and defecation frequency; however, their specific roles in these processes remain poorly understood. We hypothesized that variations in specific human milk proteins are associated with differences in stool frequency among exclusively breastfed infants.
Zhan‐Hua Li, Zhen‐Rong Xie, Meng Li, Jing‐Jing Xiong, Mei Liu, Yong‐Kun Huang   +5 more
wiley   +1 more source

Capturing Multiscale Dynamics of Aortic Valve Calcification with a Coupled Fluid-Structure and Systems Biology Model. [PDF]

ACS Omega
Quan M, Xie T, Harris LA, Luo H.
europepmc   +1 more source

Bacteriophages hijack 2',3'-cNMPs to enhance transposase-mediated phage DNA integration in <i>Acinetobacter baumannii</i>. [PDF]

Sci Adv
Cui B, Ling X, Peng G, Guo Q, Kong X, Wang R, Ma Y, Deng P, Cai H, Wang X, Deng Y.   +10 more
europepmc   +1 more source