Results 81 to 90 of about 77,168 (243)

Effect of retinal detachment on vitreous cyclic guanosine monophosphate (cGMP)(pmol/ml) levels

, 2011
Copyright information:Taken from "Cyclic GMP in the pig vitreous and retina after experimental retinal detachment"Molecular Vision 2008;14():255-261.Published online 04 Feb 2008PMCID:PMC2254957.
Marijke A.M. Lemmens (87953), Aize Kijlstra (52532), Ellen C. La Heij (87952), Roselie M.H. Diederen (87951), Fred Hendrikse (87955), Jan de Vente (87954)   +5 more
core   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes

Scientific Reports
Recent clinical trials of drugs enhancing cyclic guanosine monophosphate (cGMP) signaling for cardiovascular diseases have renewed interest in cGMP biology within the kidney.
Nelli Rutkowski, Frederik Görlitz, Eva Wiesner, Julia Binz-Lotter, Susanne Feil, Robert Feil, Thomas Benzing, Matthias J. Hackl   +7 more
doaj   +1 more source

A new plant guanosine cyclase ZjGC found from jujube regulates growth and development via endogenous hormones

Frontiers in Plant Science
Cyclic guanosine monophosphate (cGMP) is an important second messenger involved in many physiological processes. Guanylate cyclase (GC), the key synthetase of cGMP, has been identified in many microorganisms and mammals, but very few in plants for their ...
Xin Zhao, Haonan Cao, Yao Liu, Junyan Mai, Fangyuan Yang, Zhiguo Liu, Zhiguo Liu, Mengjun Liu, Mengjun Liu   +8 more
doaj   +1 more source

Development of a cGMP recorder with chemical labeling

Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger, that regulates the cardiovascular system, brain functions and is involved in many pathological processes.
Johnsson, Kai, Bühler, Bastian, Zhang, Yuqi   +2 more
core   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad, Jeanne du Fay de Lavallaz, Michael J. Zhang, Thanat Chaikijurajai, Bo Ye, Prabhjot S. Nijjar, Julie A. Lahiri, Cindy M. Martin, Tamas Alexy, Markus Meyer   +9 more
wiley   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Spectrofluorimetric determination of cyclic guanosine monophosphate in human nasal secretions: evaluating levels in healthy individuals and patients with olfactory dysfunction

BMC Chemistry
Cyclic guanosine monophosphate (cGMP) is a second messenger involved in olfactory signal transduction. cGMP levels modulate the sensitivity of olfactory neurons and are implicated in olfactory dysfunctions.
Mohamed H. Abdelazim, Faisal Alsenani, Adnan Alharbi, Fahad H. Baali, Abdulaziz H. Baali, Maram H. Abduljabbar, Reem M. Alnemari, Majed A. Algarni   +7 more
doaj   +1 more source

Donkwa Enriched With Goron‐Tula (Azanza garckeana) Modulates Sexual Behavior and Activity of Enzymes Linked With Erectile Dysfunction in High‐Fat Diets/ Streptozotocin‐Induced (STZ/HFD) Diabetic Rats

Food Chemistry International, EarlyView.
(A) Mount number, (B) mount latency, (C) intromission number, and (D) intromission latency are the parameters of sexual behavior. Met = metformin. D100 = 100 Donkwa. D90G10 = 90% Donkwa + 10% Goron‐Tula. D85G15 = 85% Donkwa + 15% Goron‐Tula. D80G20 = 80% Donkwa + 20% Goron‐Tula. The mean ± standard error of the mean (SEM) expressed the results. *Values
O. T. Mamukuyomi, O. S. Ijarotimi, A. A. Badejo   +2 more
wiley   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source