Results 181 to 190 of about 33,931 (282)

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, Volume 104, Issue 6, Page 604-615, September 2026.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Effectiveness of Onabotulinumtoxin-A in Patients with Chronic Migraine and Previous CGRP-mAb Treatment Failure: A Multicentre 6-Month Real-World Experience. [PDF]

Toxins (Basel)
Silvestro M, Albanese M, Orologio I, Iannone LF, Pistoia F, Battistini S, Avino G, Petracca M, Romozzi M, Ornello R, Centonze D, Sacco S, Russo A, On Behalf Of The Italian Headache Registry RICe Study Group.   +13 more
europepmc   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

CGRP: the immune system's double agent - context-dependent roles in inflammation, resolution and cancer. [PDF]

Front Immunol
Assas MB.
europepmc   +1 more source

Processionary Moth Exposure in Europe: Toxic–Irritant and Immunoglobulin E‐Mediated Endotypes, Diagnosis and Management

Clinical &Experimental Allergy, Volume 56, Issue 9, Page 1017-1030, September 2026.
Most reactions are toxic–irritant, driven by epithelial injury and neuro‐inflammatory activation. IgE‐mediated allergy is less common but may cause immediate systemic reactions. Endotype differentiation guides diagnosis, risk stratification and management.
Prasad Dasari, Josefine Haas, Wolfgang Rohe, Kai Gloyna, Christoph Viebahn, Susann Forkel, Michael Szardenings, Christine Stadelmann, Michael P. Schön, Timo Buhl   +9 more
wiley   +1 more source

Optogenetic Dissection of Sensory Neuron-Macrophage Interactions in Psoriasiform Skin Inflammation: Advances Based on In Vivo Calcium Imaging Techniques. [PDF]

Exp Dermatol
Zheng P, Chen L.
europepmc   +1 more source

Amylin: A Multi‐Functional Pancreatic Hormone—A Review

Diabetes, Obesity and Metabolism, Volume 28, Issue S5, Page 27-41, September 2026.
ABSTRACT Amylin is a pancreatic beta‐cell hormone that sits at a systems hub connecting key aspects of energy metabolism. Amylin physiologically controls satiation, slows gastric emptying and limits postprandial glucagon release, while its actions also link homeostatic eating controls with reward driven behaviours via defined central nervous system ...
Christelle Le Foll, Thomas A. Lutz
wiley   +1 more source

Neural checkpoint therapy in lung cancer. [PDF]

Trends Cancer
Das G, Zhao H, Wong STC.
europepmc   +1 more source

Migraine and Work‐Disability: New Treatments Reduce Work‐Related Burden Among Migraine Population

European Journal of Neurology, Volume 33, Issue 9, September 2026.
Migraine is a disabling disease with a substantial hidden work‐related burden, often underestimated by standard patient‐reported outcome measures. In this study, patients treated with anti‐CGRP monoclonal antibodies showed a reduction in monthly migraine days and acute medication use, together with an improvement in work‐related burden as measured by ...
Danilo Antonio Montisano, Gloria Vaghi, Claudia Altamura, Alessandra Parisi, Roberto De Icco, Marilena Marcosano, Alessia Marcassoli, Erika Guastafierro, Michele Corrado, Domenico D'Amico, Grazia Sances, Fabrizio Vernieri, Cristina Tassorelli, Alberto Raggi, Licia Grazzi   +14 more
wiley   +1 more source

Clinical characteristics and exploratory serum biomarker findings in vestibular migraine: a cross-sectional case-control study. [PDF]

Front Neurol
Liu B, Zhang D, Zhang L, Zhang Y, Guan X.   +4 more
europepmc   +1 more source