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CGRP monoclonal antibodies and CGRP receptor antagonists (Gepants) in migraine prevention
Migraine is a prevalent and disabling neurological disease. Its preventive treatment for decades has been rather limited due to the absence of disease-specific therapies with limited efficacy and tolerability. The advances made in migraine research have led to the discovery of the calcitonin gene-related peptide (CGRP) and its role in migraine ...Edoardo, Caronna +3 more
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Headache Currents, 2004
Calcitonin Gene‐Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine BACKGROUND: Calcitonin gene‐related peptide (CGRP) may have a causative role in migraine. We therefore hypothesized that a CGRP‐receptor antagonist might be effective in the treatment of migraine attacks.
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Calcitonin Gene‐Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine BACKGROUND: Calcitonin gene‐related peptide (CGRP) may have a causative role in migraine. We therefore hypothesized that a CGRP‐receptor antagonist might be effective in the treatment of migraine attacks.
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CGRP as the target of new migraine therapies — successful translation from bench to clinic
Nature Reviews Neurology, 2018L. Edvinsson +3 more
semanticscholar +1 more source
2010
Summary Aims and motivation In this thesis the role of endogene Calcitonin-gene related peptide (CGRP) in the kidney is examined. For this purpose, we examined the CGRP release from renal afferences in vitro. We compared healthy animals to animals with an induced glomerulonephritis.
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Summary Aims and motivation In this thesis the role of endogene Calcitonin-gene related peptide (CGRP) in the kidney is examined. For this purpose, we examined the CGRP release from renal afferences in vitro. We compared healthy animals to animals with an induced glomerulonephritis.
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Nihon rinsho. Japanese journal of clinical medicine, 1993
Endothelin-1 is now known to synthesized in the kidney and influence the renal function. ET-1 mRNA was detected in glomerulus and inner medullary collecting ducts using RT-PCR technique. ETA receptor mRNA was detected only in glomerulus, vasa recta bundle, and arcuate artery.
Y, Terada, K, Tomita, F, Marumo
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Endothelin-1 is now known to synthesized in the kidney and influence the renal function. ET-1 mRNA was detected in glomerulus and inner medullary collecting ducts using RT-PCR technique. ETA receptor mRNA was detected only in glomerulus, vasa recta bundle, and arcuate artery.
Y, Terada, K, Tomita, F, Marumo
openaire +1 more source