Results 21 to 30 of about 338,127 (290)
CASA MORTUÁRIA E CREMATÓRIO VILA-CHÃ – PENAJÓIA
, 2021 Todos temos vidas diferentes e diferentes formas de encarar a mesma, no entanto, existe uma condição que é comum a: a finitude. A morte chega para todos os seres vivos, nos quais está incluído o Homem, no entanto, o Homem tem consciência, é um ser espiritual e por isso encara este fenómeno de forma diferente...
openaire +2 more sources
Opiniães, 2020 Resenha de Chã (2018), de Enoo Miranda. As palavras do poeta são um rio impregnados de imaginário imagéticos. Tudo um dia foi assim. Tudo hoje continua assim.Intensidade não significa crueza de metáforas cotidianas, mas a vida está cheia dessas proezas.
openaire +2 more sources
Basal Ganglia MRS and Apgar Scores Correlation
Pediatric Neurology Briefs, 1999 Brain metabolite levels were measured by proton magnetic resonance spectroscopy (MRS) and included N-acetylaspartate (NAA), creatine (Cr), choline (Cho), and lactate and the ratios NAA to Cho and Cr (NAA-Cho-Cr), NAA-Cr, NAA-Cho, and Cho-Cr.
J Gordon Millichap
doaj +1 more source
Text mining of CHO bioprocess bibliome: Topic modeling and document classification
PLoS ONE, 2023 Chinese hamster ovary (CHO) cells are widely used for mass production of therapeutic proteins in the pharmaceutical industry. With the growing need in optimizing the performance of producer CHO cell lines, research on CHO cell line development and ...
Qinghua Wang +3 more
doaj +2 more sources
CD300LG improves the cytotoxic activity of CIK
Central European Journal of Immunology, 2017 To investigate the effect of CD300LG-γ induction on the cytotoxic activity of CIK. Eukaryotic expression plasmid hCD300LG-γ/pEGFP-C3, which can express human CD300LG-γ, was constructed and transfected into CHO cells by lipofectamine.
Qiuyue Wang +6 more
doaj +1 more source
Biological Role of Pazopanib and Sunitinib Aldehyde Derivatives in Drug-Induced Liver Injury
Metabolites, 2022 Tyrosine kinase inhibitors pazopanib and sunitinib are both used to treat advanced renal cell carcinoma but expose patients to an increased risk of hepatotoxicity.
Maud Maillard +9 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2018 The aim of this study was to test the hypothesis that reduced pre-exercise carbohydrate (CHO) availability potentiates fat oxidation after an exhaustive high-intensity exercise bout. Eight physically active men underwent a high-intensity exercise (∼95% V̇
G.A. Ferreira +6 more
doaj +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype
Journal of Pharmacological Sciences, 2004 Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi +5 more
doaj +1 more source