Results 171 to 180 of about 3,615 (181)

Hypoxia-induced ALKBH5 aggravates synovial aggression and inflammation in rheumatoid arthritis by regulating the m6A modification of CH25H

Clinical Immunology
Previous studies have shown that epigenetic factors are involved in the occurrence and development of rheumatoid arthritis (RA). However, the role of N6-methyladenosine (m6A) methylation in RA has not been determined. The aim of this study was to investigate the role and regulatory mechanisms of hypoxia-induced expression of the m6A demethylase alkB ...
Danping, Fan, Qishun, Geng, Bailiang, Wang, Xing, Wang, Ya, Xia, Liwen, Yang, Qian, Zhang, Tingting, Deng, Yuan, Xu, Hongyan, Zhao, Bin, Liu, Cheng, Lu, Xiaofeng, Gu, Cheng, Xiao   +13 more
openaire   +2 more sources

CH25H Promotes Allergen-elicited Airway Inflammation and Airway Epithelial Remodeling

American Journal of Respiratory and Critical Care Medicine
X. Wang, K. Zheng, M. Lee, G. Huang, M. Mandanas, D. Dwyer, N. Barrett   +6 more
openaire   +1 more source

Su1871 Decreased Fibrogenesis in CH25H−/− Mice in a Newly Developed Mouse Model of Intestinal Fibrosis

Gastroenterology, 2016
Tina Raselli, Annika Wyss, Céline Mamie, Gerhard Rogler, Martin Hausmann, Benjamin Misselwitz   +5 more
openaire   +1 more source

Pathogenic Mycobacterium Upregulates Cholesterol 25-Hydroxylase (CH25H) to Promote Granuloma Development via Foam Cell Formation

2023
Shuang Zhou, Xin Wen, Ding Zhang, Dan Li, Cairong Ding, Jingrui Song, Weifeng Huang, Zhu Jin, Ziwei Zhou, Xuan Xia, Bo Yan, Jin Chao, Shanshan Han, Hankun Wang, Jacqueline Gonzales, Laura E. Via, Lu Zhang, Decheng Wang   +17 more
openaire   +1 more source

G protein–coupled receptor 183 (GPR183; EBI2); cholesterol 25 hydroxylase (CH25H)

Science-Business eXchange, 2011
openaire   +1 more source

Resistance to silicosis progression in mice with Ch25h downregulation: The involvement of NLRP3 inflammasome

The International Journal of Biochemistry & Cell Biology
Meiqi Sun, Hua Fang, Jiashu Zhang, Mengyao Wang, Peng Jiang, LiLi Ma, Huanyu Jin, Wei Zhang   +7 more
openaire   +1 more source

Cholesterol Promotes Chemoresistance in Colorectal Cancer Through the Lox1/Ch25h/Cyp7b1 Axis

kehua huang, Jieshen Huang, Huang Luyao, Haixia Cheng, Jiasheng Feng   +4 more
openaire   +1 more source

Saikosaponin A ameliorates ulcerative colitis by targeting the CH25H/25-OHC axis to inhibit NLRP3 inflammasome in macrophages

Phytomedicine
Xue Yang, Jinni Yang, Anhui Wang, Yuan Zheng, Jiachun Lin, Ziwen Kong, Yuan Tian, Haijuan Dong, Zunjian Zhang, Rui Song   +9 more
openaire   +1 more source

A U-Net–Based Automated Fluorescence and Morphological Analysis of CH25H Knockdown and Overexpressing Cell Lines

2025 4th International Symposium on Computer Applications and Information Technology (ISCAIT)
Zhengqi Liang, Fengkai Luan
openaire   +1 more source

Loss of the cholesterol metabolizing enzyme Ch25h protects against cigarette smoke-induced COPD.

2017
Conlon, T.M., Jia, J., Gao, J., Heinzelmann, K., Tasdemir, D., Bayram, H., Eickelberg, O., Yildirim, A.Ö.   +7 more
openaire   +1 more source