Results 61 to 70 of about 3,615 (181)
Die Genetik des Lipidstoffwechsels als Risikofaktor für kognitive Defizite bei der Parkinson-Krankheit [PDF]
, 2020 Die Parkinson-Krankheit gehört zu den Basalganglienerkrankungen und ist nach der Alzheimer-Krankheit die zweithäufigste neurodegenerative Erkrankung.
Söling, Charlotte
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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner
Journal of Neuroinflammation, 2020 Background Genome-wide association studies of Alzheimer’s disease (AD) have implicated pathways related to lipid homeostasis and innate immunity in AD pathophysiology.
Man Ying Wong +13 more
doaj +1 more source
Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]
, 2017 The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul +5 more
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Animal Research and One Health, EarlyView.ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang +8 more
wiley +1 more source
Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra. [PDF]
, 2019 The bacterium Mycobacterium tuberculosis (Mtb) causes tuberculosis and is responsible for more human mortality than any other single pathogen1. Progression to active disease occurs in only a fraction of infected individuals and is predicted by an ...
Chen, Katherine J +6 more
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Transcriptome profiling of IL-17A preactivated mesenchymal stem cells: a comparative study to unmodified and IFN-gamma modified mesenchymal stem cells [PDF]
, 2017 Published 15 February 2017Human mesenchymal stem cells pretreatment with IL-17A (MSC-17) potently enhances T cell immunosuppression but not their immunogenicity, in addition to avidly promoting the induction of suppressive regulatory T cells.
Coates, P.T. +4 more
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The Thymus Regeneration Paradox: The Search for Stemness in an Involuting Organ
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT The thymus is emerging as a model for studying organ regeneration and stem cell biology. While research has long focused on how antigen‐presenting cells shape the T cell repertoire, recent discoveries unveil a far richer cellular landscape that challenges long‐held views of thymus structure and function. This review traces the history of early
Roberta Ragazzini, Paola Bonfanti
wiley +1 more source
Neural Regeneration Research, 2023 Astrocytes are important cellular centers of cholesterol synthesis and metabolism that help maintain normal physiological function at the organism level. Spinal cord injury results in aberrant cholesterol metabolism by astrocytes and excessive production
Chen Chen +9 more
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Animal Research and One Health, Volume 4, Issue 1, Page 105-119, February 2026.Multi‐omics analysis revealed that FOS supplementation increased the abundance of Phascolarctobacterium, GCA‐900066575, Shuttleworthia, Olsenella, Eubacterium_hallii_group while decreasing Alistipes. It also influenced the metabolism of S‐lactoylglutathione, p‐cresol glucuronate, 2‐phenylethanol glucuronide, propionic acid, dulcitol, and inhibited the ...
Dan Song +11 more
wiley +1 more source
Viruses, 2023 Marek’s disease virus (MDV) causes a deadly lymphoproliferative disease in chickens, resulting in huge economic losses in the poultry industry. It has been suggested that MDV suppresses the induction of type I interferons and thus escapes immune control.
Nitin Kamble +6 more
doaj +1 more source