Results 111 to 120 of about 34,461 (204)

Exploring Biological Properties of Manganese(II)‐Phenanthroline‐Based Complexes: In Vitro Insights

ChemistrySelect, Volume 11, Issue 29, 3 August 2026.
Four Mn(II) complexes with phenanthroline derivatives were studied. These compounds were tested against several parasites and different human cancer cells. Despite its cytotoxicity on breast cancer, DNA seems not to be the main biological target. These complexes can drive the design and development of new metal‐based agents with improved biological ...
Roberto S. Silva, Marcos V. Palmeira‐Mello, Mikaelly P. Caet, Celisnolia M. Leite, Arieli B. Portugal, Pedro H. Machado, Alexandre B. Carvalho, Isabel Correia, Leonardo M. Moreira, Thatiana L. B. V. Simão, Elena Lasunskaia, Michelle F. Muzitano, José L. Nepomuceno‐Silva, João L. M. Wanderley, Javier Ellena, Alzir A. Batista, Mario S. Schultz   +16 more
wiley   +1 more source

Exploring the BICC1 Interactome in HEK293T Cells: Insights Into RNA‐Mediated Protein Networks and Biomolecular Condensates

FASEB BioAdvances, Volume 8, Issue 8, August 2026.
Workflow for BICC1 interactome characterization in HEK293T cells. Cells expressing FLAG‐tagged BICC1 (full‐length or ΔSAM) were subjected to co‐immunoprecipitation under RNA‐preserved (−) or RNase‐treated (+) conditions (1). Interacting proteins were identified by LC–MS/MS (2) and analyzed through protein–protein interaction networks and functional ...
Heloísa Monteiro do Amaral‐Prado, Gabriela Alves Moreira, Cristiane Santos, Fernando Henrique Bosso, Felipe Eduardo Ciamponi, Guilherme Oliveira Barbosa, Mario Henrique Bengtson, Katlin Brauer Massirer   +7 more
wiley   +1 more source

Egg‐Carrying and Cheliceral Comb in Ibaloniinae Harvestmen From the Solomon Islands (Opiliones: Podoctidae)

Austral Entomology, Volume 65, Issue 3, August 2026.
ABSTRACT Four new species of Ibaloniinae harvestmen are described from the Solomon Islands, Melanesia. Based on the original diagnosis of Euibalonius Roewer, 1915, and description of E. maculatus (Roewer, 1915), this material appeared related to that genus. However, examination of syntype photographs of the type species E.
Adriano B. Kury, Glauco Machado, Bruno A. Buzatto, Esau Kekeubata, Miguel Medrano   +4 more
wiley   +1 more source

Prevalence of Chagas Disease Among Blood Donors in Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto Nigeria

Sokoto Journal of Medical Laboratory Science, 2017
Transfusion-transmissible infections (TTIs) are the greatest threats to blood transfusion safety and pose a serious public health problem in Nigeria.
Onuigwe, Festus Uchechukwu *, Udomah, F.P., Yakubu, Abdulrahaman, Isaac, Zama, Adias, Teddy Charles, Ibrahim, Kwaifa, Buhari, Hauwa, Okwesili, Augustine, Ahmed, Marafa , Imoru, Momodu, Erhabor, Osaro, Bagudo, Aliyu, Okorie, Hope
doaj  

Identification of a Benzenesulfonylpiperazine Derivative With In Vivo Efficacy Against Visceral Leishmaniasis

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
This work highlights the satisfactory pharmacokinetic profile of two benzenesulfonylpiperazine lead candidates, followed by in vivo assessment in a murine model of visceral leishmaniasis. This assessment identified compound 2 as moderately active at a lower dose, but its efficacy increased at higher doses, though with concerns regarding safety.
Thibault Joseph William Jacques Dit Lapierre, Mariza Gabriela Faleiro de Moura Lodi Cruz, Guilherme Freitas de Lima Hercos, Rafael Consolin Chelucci, Simone Michelan‐Duarte, Gisele Barbosa, Analu R. Costa, Miguel Angel Chávez‐Fumagalli, Paula Derksen Macruz, Eduardo Jorge Pilau, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Silvane Maria Fonseca Murta, Celso de Oliveira Rezende Júnior   +13 more
wiley   +1 more source

Integrating Artificial Intelligence Into Drug Discovery From Medicinal Plants: Current Applications and Infrastructural Challenges

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
This review presents a systems‐oriented roadmap for integrating artificial intelligence into medicinal plant drug discovery to overcome persistent bottlenecks like extract complexity. It highlights that advancing toward reproducible therapeutics requires making phytochemical datasets AI‐ready via rigorous harmonization and phyto‐centric foundational ...
Amit Gangwal, Azim Ansari, Mohd Usman Mohd Siddique, Jyotiram Sawale, Suhas Padmane, Raju Wadekar   +5 more
wiley   +1 more source

Prevalence of Peri‐Implantitis Around Zirconia Implants: A Systematic Review and Meta‐Analysis of Current Evidence

Clinical Implant Dentistry and Related Research, Volume 28, Issue 4, August 2026.
ABSTRACT Background Zirconia implants (ZIs) have emerged as a metal‐free alternative to titanium implants (TIs) because of their favorable esthetic and biological properties. However, the prevalence of peri‐implantitis associated with ZIs and the potential influence of implant material on peri‐implant disease remain unclear.
Vittorio Moraschini, João Baptista de Moraes, Alice Maria de Oliveira Silva, Alexandre Marques Paes da Silva, Rafael Seabra Louro, Eduardo José Veras Lourenço, Victoria L. Souza Costa, Jamil Awad Shibli   +7 more
wiley   +1 more source

Multi‐angle, cross‐domain fusion strategy enhances automated insect identification and hierarchical categorization: a case study on assassin bugs (Hemiptera: Reduviidae)

Cladistics, Volume 42, Issue 4, Page 358-373, August 2026.
Abstract Automated insect identification systems hold significant value for biodiversity monitoring, pest management, citizen science initiatives and systematic studies, particularly in an era of declining expertise in insect taxonomy. However, current deep learning approaches often rely on standardized specimen photos from limited‐angles and ...
Xinkai Wang, Huaiyu Liu, Zhuo Chen, Yisheng Zhao, Yingqi Liu, Haoyang Xiong, Yuange Duan, Fang Song, Wanzhi Cai, Xuankun Li, Hu Li   +10 more
wiley   +1 more source

Anisocoria na fase crônica da doença de Chagas

Revista da Sociedade Brasileira de Medicina Tropical, 1995
Para verificar a freqüência de anisocoria em portadores da fase crônica da doença de Chagas foi feito estudo prospectivo e duplo cego. Foram submetidos a exame oftalmológico 131 pacientes com sorologia positiva para doença de Chagas e 138 indivíduos com ...
João Antônio Prata, João Antônio Prata Júnior, Cleudson Nery de Castro, Vanize Macedo, Aluízio Prata   +4 more
doaj  

Evaluation of a Novel Peptide‐Based ELISA for the Serological Diagnosis of Trypanosoma cruzi Infection

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Chagas disease is a neglected tropical disease endemic in most of the Americas, caused by Trypanosoma cruzi. New serological tests with improved performance are urgently needed for accurate diagnosis of T. cruzi infections. We evaluated here the performance of a novel peptide ELISA based on highly conserved parasite antigens, using a large ...
Alicia Majeau, Julio Vladimir Cruz‐Chan, Etienne Waleckx, Eric Dumonteil, Claudia Herrera   +4 more
wiley   +1 more source