A series of 5‐nitroimidazole‐1,2,3‐triazole hybrids was synthesised and evaluated for antitrypanosomatid activity to assess their potential as treatments against leishmaniasis and trypanosomiasis. No notable in vitro activity against Leishmania was detected.
Liandi Ferreira +4 more
wiley +1 more source
Can Vaccination Prevent the Development of Chagas Disease Cardiomyopathy? [PDF]
Cunha-Neto E, Santoro Rosa D.
europepmc +1 more source
Pyridyl‐Imidazopyridine Derivatives Displaying Submicromolar Activity Against Trypanosoma cruzi
Previously reported pyridyl‐thiazoles and highly active imidazopyridines against Trypanosoma cruzi inspired the design of a new series of pyridyl‐substituted imidazopyridines. Among the synthesized compounds, 5h emerged as the most promising derivative, displaying potent trypanocidal activity (EC50 = 0.16 μM), excellent selectivity (SI > 1250), and ...
Ana Carolina Rocha Barreto +9 more
wiley +1 more source
Evidence Lacking for Endemic Chagas Disease in the United States (Response). [PDF]
Beatty NL +4 more
europepmc +1 more source
Chagas Disease: An Opportunistic Infection in AIDS. [PDF]
Popovic K +4 more
europepmc +1 more source
Development of an ICF Core Set for adults with Chagas disease: a qualitative study capturing patients' perspective on functioning. [PDF]
Ottone NCS +7 more
europepmc +1 more source
Anticoagulation for Atrial Fibrillation after Resolution of Dengue Haemorrhagic Fever [PDF]
Henrique Horta Veloso
doaj +1 more source
Evaluation of Quality of Care in Chagas Disease Cardiomyopathy. [PDF]
Gulayin PE +10 more
europepmc +1 more source
Physical activity and subclinical atherosclerosis in chronic Chagas disease: a cross-sectional study. [PDF]
Diferenz EM +11 more
europepmc +1 more source
Host immune responses and immune evasion mechanisms in Trypanosoma cruzi: implications for the immunopathogenesis of Chagas disease. [PDF]
Andrade CMP.
europepmc +1 more source

