Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Serum cytokines and tissue doppler imaging as markers of prognosis of chronic myocarditis due to chagas disease. [PDF]
Soares ISB +7 more
europepmc +1 more source
Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák +8 more
wiley +1 more source
Evaluation of the autonomic nervous system in autochthonous patients from Amazon with acute Chagas disease treated with benznidazole. [PDF]
Hosannah da Silva E Silva MR +12 more
europepmc +1 more source
Non-Coding RNAs as Emerging Biomarkers in Leishmaniasis and Chagas Disease. [PDF]
Ramos Juárez E +15 more
europepmc +1 more source
Chagas Disease, an Endemic Disease in the United States. [PDF]
Beatty NL +4 more
europepmc +1 more source
In Silico Design and Evaluation of TcGAPDH as a Vaccine Against Chagas Disease: A Reverse Vaccinology Approach. [PDF]
Nava-Cuamatzi V +4 more
europepmc +1 more source
Mechanistic Exploration of N,N'-Disubstituted Diamines as Promising Chagas Disease Treatments. [PDF]
Recio-Balsells AI +9 more
europepmc +1 more source

