21-Hydroxylase gene mutant allele CYP21A2∗15 strongly linked to the resistant HLA haplotype B∗14:02-DRB1∗01:02 in chronic Chagas disease [PDF]
We previously reported protective haplotype HLA-B*14:02-DRB1*01:02 against chronic Chagas disease in Bolivia. The V281L mutant allele of the 21-Hydroxylase gene, CYP21A2*15, is reported to be located in the Class III region of the Human leukocyte antigen
Gianella, Alberto +10 more
core +1 more source
In the Spotlight—Established Researcher
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Rodrigo Nunes‐da‐Fonseca
wiley +1 more source
Across selected bullfrog farms in major Chinese production regions, 106 intestinal ARG subtypes were detected, with tetracycline and sulfonamide resistance genes predominating and clear farm‐level variation. High‐risk ARGs, including ermB, floR, and qnrA, were associated with heavy metals, MGEs, and opportunistic pathogens. These findings highlight the
Yang Xu +7 more
wiley +1 more source
Chagas disease and systemic autoimmune diseases among Bolivian patients in Switzerland
BACKGROUND Chronic cardiomyopathy occurs in 20-40% of the patients with Chagas disease. Autoimmune mechanisms may contribute to its pathogenesis. We diagnosed several cases of systemic autoimmune diseases among Bolivian migrants in Geneva with a high ...
Yves Jackson +4 more
doaj +1 more source
Chagas disease : neglected parasitic infections in the United States [PDF]
Chagas disease is a preventable infection caused by the parasite Trypanosoma cruzi and spread by infected insects called triatomine bugs, also known as \u201ckissing bugs.\u201d The initial infection usually does not cause severe symptoms and is often ...
core
Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients. [PDF]
BACKGROUND: Chagas disease results from infection with the diploid protozoan parasite Trypanosoma cruzi. T. cruzi is highly genetically diverse, and multiclonal infections in individual hosts are common, but little studied.
Torrico, Faustino +52 more
core +1 more source
Abstract Purpose To evaluate the evidence of internal structure validity of the nursing outcome (NO) “Mechanical Ventilation Weaning Response: Adult (0412)” of the NOs classification for critically ill COVID‐19 patients. Methods A methodological study focused on internal structural validation, part of a multicenter study, was carried out in the ...
Aline Batista Maurício +8 more
wiley +1 more source
Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil
Chagas disease in patients with HIV infection represents a potentially serious event with high case fatality rates. This study describes epidemiological and clinical aspects of deaths related to Chagas disease and HIV/AIDS coinfection in Brazil, 1999 ...
Francisco Rogerlândio Martins-Melo +3 more
doaj +1 more source
Mapping of Chagas disease research: analysis of publications in the period between 1940 and 2009
INTRODUCTION: Publications are often used as a measure of success in research work. Chagas disease occurs in Central and Southern America. However, during the past years, the disease has been occurring outside Latin America due to migration from endemic ...
José Manuel Ramos +3 more
doaj +1 more source
International meeting: New diagnostic tests are urgently needed to treat patients with Chagas disease. [PDF]
Trypanosoma cruzi infection is often not detected early on or actively diagnosed, partly because most infected individuals are either asymptomatic or oligosymptomatic.
Campaign for Access to Essential Medicines
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