Results 61 to 70 of about 114,131 (308)

Identification of Potential Trypanosoma cruzi Trans-Sialidase Inhibitors by Computational Drug Repositioning Approaches

Scientia Pharmaceutica
Chagas disease, caused by the parasitic protozoan Trypanosoma cruzi (T. cruzi), represents a worldwide public health issue. To date, there is no efficient treatment to combat this pathology, and the only drugs available are usually toxic to the patient ...
Miguel A. Uc-Chuc, Nohemi Cigarroa-Toledo, Karla Y. Acosta-Viana, José I. Chan-Pérez, Juan C. Pineda-Cortes, Hernán de J. Villanueva-Alonzo   +5 more
doaj   +1 more source

Treatment and seroconversion in a cohort of children suffering from recent chronic Chagas infection in Yoro, Honduras

, 2009
Between 1999-2002, Médécins Sans Frontières-Spain implemented a project seeking to determine the efficacy and safety of benznidazole in the treatment of recent chronic Chagas disease in a cohort of seropositive children in the Yoro Department, Honduras ...
Andrea Marchiol, Ponce, Carlos, Josep M Escribà, Lima, M Angeles, Escribà, Josep M., Escribà, Josep M, Alberto de Dios Romero, Elisa Ponce, Pedro Albajar Viñas, Romero, Alberto de Dios, Marchiol, Andrea, Glòria Bassets, Concepción Zúniga, M Angeles Lima, Zúniga, Concepción, Pedro Pablo Palma, Carlos Ponce, Lima, M. Angeles, Viñas, Pedro Albajar, Ponce, Elisa, Bassets, Glòria, Palma, Pedro Pablo   +21 more
core   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Poor response to tuberculosis treatment with regimens without rifampicin in immunosuppressed AIDS patients

Brazilian Journal of Infectious Diseases
A prospective study was conducted on 79 advanced immunosuppressed AIDS patients from 1997 to 1999, during which nine cases of tuberculosis (TB) were diagnosed.
M.M. O'Donnel, S. Souza Carvalho, A.J. Gadelha, M.G. Morgado, M.C.G. Galhardo, M.C. Lourenço, V.C. Rolla   +6 more
doaj   +1 more source

Yellow fever virus isolated from a fatal post vaccination event: an experimental comparative study with the 17DD vaccine strain in the Syrian hamster (Mesocricetus auratus)

Revista da Sociedade Brasileira de Medicina Tropical, 2004
In order to investigate the pathogenicity of the virus strain GOI 4191 that was isolated from a fatal adverse event after yellow fever virus (YFV) vaccination, an experimental assay using hamsters (Mesocricetus auratus) as animal model and YFV 17DD ...
Sueli Guerreiro Rodrigues, Amélia Paes de Andrade Travassos da Rosa, Ricardo Galler, Vera Lúcia Reis de Souza Barros, Conceição de Maria Almeida Vieira, Jorge Fernando Soares Travassos da Rosa, Raimunda do Socorro da Silva Azevedo, Márcio Roberto Teixeira Nunes, Elizabeth Salbé Travassos da Rosa, Pedro Fernando da Costa Vasconcelos   +9 more
doaj   +1 more source

Pupillometry in Chagas disease

Arquivos Brasileiros de Oftalmologia, 2018
We investigated parasympathetic innervation abnormalities of the iris sphincter and ciliary muscles in chronic Chagas disease by measuring pupillary diameter and intraocular pressure.A group of 80 patients with Chagas disease was compared with 76 healthy individuals without chagasic infection.
Vargas, Diva, Castro, Cleudson
openaire   +4 more sources

Modified Neumann incision for implant placement in overdentures: Case series of a less invasive alternative

Clinical Advances in Periodontics, EarlyView.
Abstract Background Conventional envelope flap techniques for implant placement in edentulous mandibles are associated with greater postoperative morbidity, especially in elderly patients or those with anatomical limitations. Minimally invasive alternatives aim to preserve soft tissues and reduce complications, enhancing clinical predictability ...
Lucas Jardim da Silva, Laura Lourenço Morel, Luciana de Rezende Pinto, Otacílio Luiz Chagas‐Júnior, Jamil Awad Shibli, Fernanda Faot   +5 more
wiley   +1 more source

Chagas, Carlos -- 1977-91 -- Correspondence, Individual -- letter, 1982-08-11

, 1982
Letter from Chagas, Carlos to Sabin, Albert B.
Chagas, Carlos
core  

Effects of Dehulling and Extrusion‐Cooking on the Nutritional and Physicochemical Properties of Navy Bean (Phaseolus vulgaris L.) Flours

ChemFoodChem, EarlyView.
Dehulling combined with twin‐screw extrusion improves the nutritional and functional properties of steam treated navy beans. Protein digestibility increases while phytic acid is reduced by 43% and trypsin inhibitors are inactivated. Enhanced expansion, solubility, and sensory quality highlight the potential of dehulled bean flours for developing ...
Albarracín M, Garzon AG, Drago SR
wiley   +1 more source

Chagas disease provider fact sheet [PDF]

What is Chagas disease? -- Where is Chagas found? -- Who is at risk? -- How is the disease transmitted? -- What are the phases of the disease?

core   +2 more sources