Results 1 to 10 of about 100,897 (251)
In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. [PDF]
, 2010 BackgroundCruzain, the major cysteine protease of Trypanosoma cruzi, is an essential enzyme for the parasite life cycle and has been validated as a viable target to treat Chagas' disease.
Brinen, Linda S +6 more
core +57 more sources
Congenital Chagas disease: A cohort study to assess molecular diagnostic methods at the Chagas disease national reference center of Argentina. [PDF]
PLoS Neglected Tropical DiseasesBackgroundTrypanosoma cruzi is a protozoan parasite which causes Chagas disease. Mother-to-child transmission is the main route of transmission in vector-free areas.
Constanza Lopez-Albizu +6 more
doaj +2 more sources
Chagas disease and immunosuppression [PDF]
Memórias do Instituto Oswaldo Cruz, 1999 Chagas disease, caused by a hemoflagellate,Trypanosoma cruzi, is a parasitic disease widelydistributed throughout Latin America. It is trans-mitted to man by hematophagous vectors (redu-viid bugs), blood transfusion and, more rarely, byoral route, laboratory accidents, and from motherto fetus.
Marcelo Simão Ferreira
openalex +6 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Chagas disease (CD) presents an ominous prognosis. The predictive value of biomarkers and new echocardiogram parameters in adjusted models have not been well studied.
Veronica G. Mendes +21 more
doaj +1 more source
Journal of Allergy and Clinical Immunology: Global, 2023 Background: Vaccination is an extremely safe public health intervention, but rare IgE-mediated adverse events must be identified to avoid the risk of anaphylaxis in the event of reexposure.
Luciana Gomes Pedro Brandão, PhD, MSc, MD +10 more
doaj +1 more source
Pediatrics In Review, 2016 Approximately 8 million people worldwide are infected by the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. After a latent period that can last years or decades, 10% to 30% of infected people develop serious complications, such as cardiomyopathy or gastrointestinal dysfunction.
Tustin, Aaron W., Bowman, Natalie M.
openaire +2 more sources
EClinicalMedicine, 2021 Background: Chagas disease (CD) remains an important endemic disease in Latin America. However, CD became globalized in recent decades. The majority of the chronically infected individuals did not receive etiologic treatment for several reasons, among ...
Alejandro M. Hasslocher-Moreno +14 more
doaj +1 more source
Stroke in Chagas disease: from pathophysiology to clinical practice [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2022 Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern.
Thaís Aparecida Reis Lage +6 more
doaj +1 more source
Tropical Medicine and Infectious Disease, 2020 Most patients with chronic Chagas disease (CD) present the indeterminate form and are at risk to develop the cardiac form. However, the actual rate of progression to the cardiac form is still unknown.
Alejandro Marcel Hasslocher-Moreno +11 more
doaj +1 more source
Medical Mycology Case Reports, 2022 We present a rare condition of mixed C. neoformans and C. gattii infection in a person living with HIV with false-negative CrAg LFA in the CSF and co-infection with paracoccidioidomycosis.
Marcela de Faria Ferreira +5 more
doaj +1 more source