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Chagas' disease. [PDF]

Clinical Microbiology Reviews, 1992
Chagas' disease, caused by Trypanosoma cruzi, is an important cause of morbidity in many countries in Latin America. The important modes of transmission are by the bite of the reduviid bug and blood transfusion. The organism exists in three morphological forms: trypomastigotes, amastigotes, and epimastigotes.
Herbert B. Tanowitz, Louis V. Kirchhoff, Douglas Simon, Stephen Morris, Louis M. Weiss, Murray Wittner   +5 more
openalex   +4 more sources

Chagas disease. [PDF]

CMAJ
Chagas disease persists as a global public health problem due to the high morbidity and mortality burden. Despite the possibility of a cure and advances in transmission control, epidemiological transformations, such as urbanisation and globalisation, and the emerging importance of oral and vertical transmission mean that Chagas disease should be ...
Billick MJ, Silverberg SL.
europepmc   +4 more sources

American trypanosomiasis and Chagas disease: Sexual transmission

International Journal of Infectious Diseases, 2019
Objective: To contribute to the discussion on the research findings indicating the sexual transmission of American trypanosomiasis and Chagas disease in humans.
Clever Gomes, Adriana B. Almeida, Ana C. Rosa, Perla F. Araujo, Antonio R.L. Teixeira   +4 more
doaj   +2 more sources

Congenital Chagas disease: A cohort study to assess molecular diagnostic methods at the Chagas disease national reference center of Argentina. [PDF]

PLoS Neglected Tropical Diseases
BackgroundTrypanosoma cruzi is a protozoan parasite which causes Chagas disease. Mother-to-child transmission is the main route of transmission in vector-free areas.
Constanza Lopez-Albizu, Carolina Inés Cura, Juan Carlos Ramirez, Pamela Peyran, Andrés Benchetrit, Emmaría Danesi, Sergio Sosa-Estani   +6 more
doaj   +2 more sources

Biomarkers and Echocardiographic Predictors of Cardiovascular Outcome in Patients With Chronic Chagas Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Chagas disease (CD) presents an ominous prognosis. The predictive value of biomarkers and new echocardiogram parameters in adjusted models have not been well studied.
Veronica G. Mendes, Lorena Rimolo, Ana Carolina B. de Lima, Roberto R. Ferreira, Luciano S. Oliveira, Lindice M. Nisimura, Samuel I. M. Horita, Andréa R. Costa, Gilberto Marcelo S. da Silva, Luiz Henrique C. Sangenis, Fernanda S. N. S. Mendes, Andrea S. Sousa, Henrique H. Veloso, Marcelo T. Holanda, Mauro F. F. Mediano, Mariana C. Waghabi, Luciana R. Garzoni, Otacílio C. Moreira, Constança Britto, Ademir B. Cunha, Alejandro Marcel Hasslocher‐Moreno, Roberto M. Saraiva   +21 more
doaj   +1 more source

Chagas Disease [PDF]

Pediatrics In Review, 2016
Approximately 8 million people worldwide are infected by the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. After a latent period that can last years or decades, 10% to 30% of infected people develop serious complications, such as cardiomyopathy or gastrointestinal dysfunction.
Tustin, Aaron W., Bowman, Natalie M.
openaire   +2 more sources

Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil

Journal of Allergy and Clinical Immunology: Global, 2023
Background: Vaccination is an extremely safe public health intervention, but rare IgE-mediated adverse events must be identified to avoid the risk of anaphylaxis in the event of reexposure.
Luciana Gomes Pedro Brandão, PhD, MSc, MD, Mari Tuyama, PhD, MSc, MD, Flávio de Carvalho, MSc, RN, Ananza Taina da Silva Santos, MSc, RN, Alberto dos Santos de Lemos, MSc, MD, Marcellus Dias da Costa, MSc, MD, Emersom Cicilini Mesquita, PhD, MSc, MD, José Cerbino-Neto, PhD, MSc, MD, Margareth Catoia Varela, MSc, Pedro Emmanuel Alvarenga Americano do Brasil, PhD, MSc, MD, Angélica Varela Rondon, MSc, MD   +10 more
doaj   +1 more source

Benznidazole decreases the risk of chronic Chagas disease progression and cardiovascular events: A long-term follow up study

EClinicalMedicine, 2021
Background: Chagas disease (CD) remains an important endemic disease in Latin America. However, CD became globalized in recent decades. The majority of the chronically infected individuals did not receive etiologic treatment for several reasons, among ...
Alejandro M. Hasslocher-Moreno, Roberto M. Saraiva, Luiz H.C. Sangenis, Sergio S. Xavier, Andrea S. de Sousa, Andrea R. Costa, Marcelo T. de Holanda, Henrique H. Veloso, Fernanda S.N.S. Mendes, Filipe A.C. Costa, Marcio N. Boia, Pedro E.A.A. Brasil, Fernanda M. Carneiro, Gilberto M.Sperandio da Silva, Mauro F.F. Mediano   +14 more
doaj   +1 more source

Stroke in Chagas disease: from pathophysiology to clinical practice [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2022
Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern.
Thaís Aparecida Reis Lage, Julia Teixeira Tupinambás, Lucas Bretas de Pádua, Matheus de Oliveira Ferreira, Amanda Cambraia Ferreira, Antonio Lucio Teixeira, Maria Carmo Pereira Nunes   +6 more
doaj   +1 more source

Progression Rate from the Indeterminate Form to the Cardiac Form in Patients with Chronic Chagas Disease: Twenty-Two-Year Follow-Up in a Brazilian Urban Cohort

Tropical Medicine and Infectious Disease, 2020
Most patients with chronic Chagas disease (CD) present the indeterminate form and are at risk to develop the cardiac form. However, the actual rate of progression to the cardiac form is still unknown.
Alejandro Marcel Hasslocher-Moreno, Sergio Salles Xavier, Roberto Magalhães Saraiva, Luiz Henrique Conde Sangenis, Marcelo Teixeira de Holanda, Henrique Horta Veloso, Andrea Rodrigues da Costa, Fernanda de Souza Nogueira Sardinha Mendes, Pedro Emmanuel Alvarenga Americano do Brasil, Gilberto Marcelo Sperandio da Silva, Mauro Felippe Felix Mediano, Andrea Silvestre de Sousa   +11 more
doaj   +1 more source