Results 1 to 10 of about 43,654 (169)

Biomarkers and Echocardiographic Predictors of Cardiovascular Outcome in Patients With Chronic Chagas Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Chagas disease (CD) presents an ominous prognosis. The predictive value of biomarkers and new echocardiogram parameters in adjusted models have not been well studied.
Veronica G. Mendes, Lorena Rimolo, Ana Carolina B. de Lima, Roberto R. Ferreira, Luciano S. Oliveira, Lindice M. Nisimura, Samuel I. M. Horita, Andréa R. Costa, Gilberto Marcelo S. da Silva, Luiz Henrique C. Sangenis, Fernanda S. N. S. Mendes, Andrea S. Sousa, Henrique H. Veloso, Marcelo T. Holanda, Mauro F. F. Mediano, Mariana C. Waghabi, Luciana R. Garzoni, Otacílio C. Moreira, Constança Britto, Ademir B. Cunha, Alejandro Marcel Hasslocher‐Moreno, Roberto M. Saraiva   +21 more
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Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil

Journal of Allergy and Clinical Immunology: Global, 2023
Background: Vaccination is an extremely safe public health intervention, but rare IgE-mediated adverse events must be identified to avoid the risk of anaphylaxis in the event of reexposure.
Luciana Gomes Pedro Brandão, PhD, MSc, MD, Mari Tuyama, PhD, MSc, MD, Flávio de Carvalho, MSc, RN, Ananza Taina da Silva Santos, MSc, RN, Alberto dos Santos de Lemos, MSc, MD, Marcellus Dias da Costa, MSc, MD, Emersom Cicilini Mesquita, PhD, MSc, MD, José Cerbino-Neto, PhD, MSc, MD, Margareth Catoia Varela, MSc, Pedro Emmanuel Alvarenga Americano do Brasil, PhD, MSc, MD, Angélica Varela Rondon, MSc, MD   +10 more
doaj   +1 more source

Benznidazole decreases the risk of chronic Chagas disease progression and cardiovascular events: A long-term follow up study

EClinicalMedicine, 2021
Background: Chagas disease (CD) remains an important endemic disease in Latin America. However, CD became globalized in recent decades. The majority of the chronically infected individuals did not receive etiologic treatment for several reasons, among ...
Alejandro M. Hasslocher-Moreno, Roberto M. Saraiva, Luiz H.C. Sangenis, Sergio S. Xavier, Andrea S. de Sousa, Andrea R. Costa, Marcelo T. de Holanda, Henrique H. Veloso, Fernanda S.N.S. Mendes, Filipe A.C. Costa, Marcio N. Boia, Pedro E.A.A. Brasil, Fernanda M. Carneiro, Gilberto M.Sperandio da Silva, Mauro F.F. Mediano   +14 more
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Stroke in Chagas disease: from pathophysiology to clinical practice [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2022
Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern.
Thaís Aparecida Reis Lage, Julia Teixeira Tupinambás, Lucas Bretas de Pádua, Matheus de Oliveira Ferreira, Amanda Cambraia Ferreira, Antonio Lucio Teixeira, Maria Carmo Pereira Nunes   +6 more
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Progression Rate from the Indeterminate Form to the Cardiac Form in Patients with Chronic Chagas Disease: Twenty-Two-Year Follow-Up in a Brazilian Urban Cohort

Tropical Medicine and Infectious Disease, 2020
Most patients with chronic Chagas disease (CD) present the indeterminate form and are at risk to develop the cardiac form. However, the actual rate of progression to the cardiac form is still unknown.
Alejandro Marcel Hasslocher-Moreno, Sergio Salles Xavier, Roberto Magalhães Saraiva, Luiz Henrique Conde Sangenis, Marcelo Teixeira de Holanda, Henrique Horta Veloso, Andrea Rodrigues da Costa, Fernanda de Souza Nogueira Sardinha Mendes, Pedro Emmanuel Alvarenga Americano do Brasil, Gilberto Marcelo Sperandio da Silva, Mauro Felippe Felix Mediano, Andrea Silvestre de Sousa   +11 more
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Mixed infection by Cryptococcus neoformans and Cryptococcus gattii and coinfection with paracoccidioidomycosis in PLHIV

Medical Mycology Case Reports, 2022
We present a rare condition of mixed C. neoformans and C. gattii infection in a person living with HIV with false-negative CrAg LFA in the CSF and co-infection with paracoccidioidomycosis.
Marcela de Faria Ferreira, Fabio Brito-Santos, Pedro Henrique Nascimento Theodoro, Marcos de Abreu Almeida, Marcia dos Santos Lazera, Luciana Trilles   +5 more
doaj   +1 more source

Key Chagas disease missing knowledge among at-risk population in Spain affecting diagnosis and treatment

Infectious Diseases of Poverty, 2021
Background Chagas disease is endemic in Latin America and, over the last few decades, due to population movements, the disease has spread to other continents. Early diagnosis and treatment are critical in terms of improving outcomes for those living with
María Romay-Barja, Laura Iglesias-Rus, Teresa Boquete, Agustín Benito, Teresa Blasco-Hernández   +4 more
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Mortality among blood donors seropositive and seronegative for Chagas disease (1996-2000) in São Paulo, Brazil: A death certificate linkage study. [PDF]

PLoS Neglected Tropical Diseases, 2017
Individuals in the indeterminate phase of Chagas disease are considered to have mortality rates similar to those of the overall population. This study compares mortality rates among blood donors seropositive for Chagas disease and negative controls in ...
Ligia Capuani, Ana Luiza Bierrenbach, Airlane Pereira Alencar, Alfredo Mendrone, João Eduardo Ferreira, Brian Custer, Antonio Luiz P Ribeiro, Ester Cerdeira Sabino   +7 more
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A protocol update for the Selenium Treatment and Chagasic Cardiomyopathy (STCC) trial

Trials, 2018
Several studies evaluating clinical forms of chronic Chagas disease show that about one-third of patients present cardiac involvement. Heart failure, sudden death and cardioembolic stroke are the main mechanisms of death in Chagas heart disease.
Marcelo Teixeira Holanda, Mauro Felippe Felix Mediano, Alejandro Marcel Hasslocher-Moreno, Sérgio Salles Xavier, Roberto Magalhães Saraiva, Andrea Silvestre Sousa, Erica Rodrigues Maciel, Fernanda Martins Carneiro, Paula Simplicio da Silva, Luiz Henrique Conde Sangenis, Henrique Horta Veloso, Claudia Santos de Aguiar Cardoso, Maria da Gloria Bonecini-Almeida, Andreia Lamoglia Souza, Eric Henrique Roma, Marcos José Azevedo, Fernanda Sant’Ana Pereira-Silva, Luis Otavio Pimentel, Marcelo Oliveira Mendes, Luciana Ribeiro Garzoni, Beatriz M. S. Gonzaga, Anna Cristina Calçada Carvalho, Pedro Emmanuel Alvarenga Americano Brasil, Gilberto Marcelo Sperandio da Silva, Tania Cremonini Araújo-Jorge   +24 more
doaj   +1 more source

Systemic antibiotics for preventing ventilator-associated pneumonia in comatose patients: a systematic review and meta-analysis

Annals of Intensive Care, 2017
Background Early-onset ventilator-associated pneumonia (EO-VAP) is the leading cause of morbidity and mortality in comatose patients. However, VAP prevention bundles focus mainly on late-onset VAP and may be less effective in preventing EO-VAP in ...
Cássia Righy, Pedro Emmanuel Americano do Brasil, Jordi Vallés, Fernando A. Bozza, Ignacio Martin-Loeches   +4 more
doaj   +1 more source