Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]
, 2017 Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto +10 more
core +2 more sources
An Arabidopsis flavonoid transporter is required for anther dehiscence and pollen development [PDF]
, 2010 FLOWER FLAVONOID TRANSPORTER (FFT) encodes a multidrug and toxin efflux family transporter in Arabidopsis thaliana. FFT (AtDTX35) is highly transcribed in floral tissues, the transcript being localized to epidermal guard cells, including those of the ...
Aarts +74 more
core +2 more sources
Silencing CHALCONE SYNTHASE in maize impedes the incorporation of tricin into lignin and increases lignin content [PDF]
, 2016 Lignin is a phenolic heteropolymer that is deposited in secondary-thickened cell walls, where it provides mechanical strength. A recent structural characterization of cell walls from monocot species showed that the flavone tricin is part of the native ...
Boerjan, Wout +12 more
core +1 more source
Chalcone Derivatives: Promising Starting Points for Drug Design
Molecules, 2017 Medicinal chemists continue to be fascinated by chalcone derivatives because of their simple chemistry, ease of hydrogen atom manipulation, straightforward synthesis, and a variety of promising biological activities.
M. N. Gomes +7 more
semanticscholar +1 more source
Advances in the Synthesis of Heteroaromatic Hybrid Chalcones
Molecules, 2023 Chalcones continue to occupy a venerated status as scaffolds for the construction of a variety of heterocyclic molecules with medicinal and industrial properties. Syntheses of hybrid chalcones featuring heteroaromatic components, especially those methods
Ajay Mallia, Joseph Sloop
doaj +1 more source
Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain [PDF]
, 2010 The consumption of flavonoid-rich foods and beverages has been suggested to limit the neurodegeneration associated with a variety of neurological disorders and to prevent or reverse normal or abnormal deteriorations in cognitive performance.
Spencer, Jeremy Paul
core +1 more source
4-({4-[(2E)-3-(2,5-Dimethoxyphenyl)prop-2-enoyl]phenyl}amino)-4-oxobutanoic Acid
Molbank, 2017 A dimethoxy amide chalcone has been synthesized in a two-step reaction. First, an amine chalcone was synthesized by the reaction of 4′-aminoacetophenone and 2,5-dimethoxybenzaldehyde using 40% NaOH solution as a catalyst in ethanol, and then followed by ...
Hery Suwito +4 more
doaj +1 more source
Synthesis and Identification of Phenyl Azochalcone & bis- azo – Chalcone Derivatives Derived from P-amino Acetophenone [PDF]
Kirkuk Journal of Science, 2018 This work involves the synthesis of different substituted amino-chalcones via claisen- schmidt condensation reaction between p-amino acetophenone and different aromatic substituted benzaldehydes. The second step involves the conversion of amino-chalcones
Zahraa Talib Ghlib +2 more
doaj +1 more source
Identifying the transporters of different flavonoids in plants [PDF]
, 2010 We recently identified a new component of flavonoid transport pathways in Arabidopsis. The MATE protein FFT (Flower Flavonoid Transporter) is primarily found in guard cells and seedling roots, and mutation of the transporter results in floral and growth ...
Beverley J. Glover +3 more
core +2 more sources
British Journal of Pharmacology, 2020 Atherosclerosis, resulting from lipid dysregulation and vascular inflammation, causes atherosclerotic cardiovascular disease (ASCVD), which contributes to morbidity and mortality worldwide.
Liv Weichien Chen +12 more
semanticscholar +1 more source