Results 111 to 120 of about 30,495 (265)

The complex of Plasmodium falciparum falcipain-2 protease with an (E)-chalcone-based inhibitor highlights a novel, small, molecule-binding site

open access: yesMalaria Journal, 2019
Background Malaria kills over 400,000 people each year and nearly half the world’s population live in at-risk areas. Progress against malaria has recently stalled, highlighting the need for developing novel therapeutics.
Jonathan M. Machin   +2 more
doaj   +1 more source

Chalcone derivatives as potential antifungal agents: Synthesis, and antifungal activity

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2015
Much research has been carried out with the aim to discover the therapeutic values of chalcone derivatives. Chalcones possess wide range of pharmacological activity such as antibacterial, antimalarial, antiprotozoal, antitubercular, anticancer, and ...
Deepa Gupta, D K Jain
doaj   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

open access: yesPlant, Cell &Environment, Volume 49, Issue 7, Page 3543-3559, July 2026.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador   +5 more
wiley   +1 more source

Bromination of Chalcone

open access: yesARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY
In this research work, a new compound, namely 2,6-dibromo-2,6-bis(bromo(phenyl)methyl)cyclohexanone (1), is synthesized and characterized for possible applications in organic electronic devices. The formation of the compound was confirmed by Fourier-transform infrared spectroscopy, 1H-, and 13C-NMR spectroscopy measurements.
Kosrat N. Kaka   +3 more
openaire   +3 more sources

Highly effective, regiospecific reduction of chalcone by cyanobacteria leads to the formation of dihydrochalcone: two steps towards natural sweetness

open access: yesMicrobial Cell Factories, 2017
Background Chalcones are the biogenetic precursors of all known flavonoids, which play an essential role in various metabolic processes in photosynthesizing organisms. The use of whole cyanobacteria cells in a two-step, light-catalysed regioselective bio-
Beata Żyszka   +2 more
doaj   +1 more source

Enhanced CO2 Coordinates the Spatial Recruitment of Diazotrophs in Rice Via Root Development

open access: yesPlant, Cell &Environment, Volume 49, Issue 7, Page 3678-3693, July 2026.
ABSTRACT Understanding the reciprocal interaction between root development and coadapted beneficial microbes in response to elevated CO2 (eCO2) will facilitate the identification of nutrient‐efficient cultivars for sustainable agriculture. Here, systematic morphological, anatomical, chemical and gene expression assays performed under low‐nitrogen ...
Junwen Zhao   +12 more
wiley   +1 more source

Etherification studies on chalcone derivatives with series of bromoalkane 1 [PDF]

open access: yes, 2008
This research is focusing on the etherification studies of chalcone derivatives with series of bromoalkanes which are bromohexane ( C6H13Br), bromoheptane (C7H15Br), bromooctane(C8H17Br), and bromononane (C9H19Br). There are two different strategy used
Boireh, Gunsiong
core  

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang   +6 more
wiley   +1 more source

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

open access: yesAngewandte Chemie, Volume 138, Issue 23, 1 June 2026.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans   +3 more
wiley   +2 more sources

Employing of 2-Acetylpyridine Based Chalcone as Hg2+ Sensing Material: Experimental and Theoretical Examination

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2022
This study reports the evaluation of 2-acetylpyridine based chalcone structure as a useful sensing material for Hg2+ ion detection by the means of UV-visible spectroscopy.
Alparslan Atahan   +3 more
doaj  

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