Results 131 to 140 of about 48,655 (255)

Development of a Novel Epoxide-Containing Trimethylenemethane Precursor for Palladium-Catalyzed Cycloadditions [PDF]

, 2019
Pd(0)-catalyzed trimethylenemethane (TMM) cycloaddition reactions have been used extensively to generate disubstituted 5-membered rings with high levels of regioselectivity, chemoselectivity, and stereoselectivity.
Paterson, Mara
core   +2 more sources

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source

Highly Lewis Acidic In Situ‐Generated Boronic Acid Ester: A Practical Catalyst for Hosomi–Sakurai Conjugate Addition, Carbonyl‐Ene Reaction, and Silane‐Mediated Amide Reduction

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
An exceptionally Lewis acidic boronic acid ester, generated in situ from pentafluorophenylboronic acid and tetrabromonaphthalenediol, catalyzes three important chemical transformations at 1–10 mol% loading: the Hosomi–Sakurai allylation of α,β‐unsaturated ketones, intermolecular carbonyl‐ene reactions, and the reductions of tertiary amides to amines ...
Ava Bousselat, Elisabeth Bats, Charbel Alkazzi, Karine Jarsale, Jacques Rouden, Jérôme Blanchet   +5 more
wiley   +1 more source

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

Advanced Science, Volume 13, Issue 25, 4 May 2026.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang, Elsa Demes‐Causse, Xujian Li, Zhenhui Guo, Hanshu Zhao, Huairong Cao, Yajing Song, Lijun Mu, Kaikai Zhang, Jing Zhang, Zhongtao Jia, Lixing Yuan, Alexis De Angeli, Jingbo Zhang   +13 more
wiley   +1 more source

Photophysics of Biological and Biomimetic Sunscreen Molecules

ChemPhotoChem, Volume 10, Issue 5, May 2026.
Recent photochemical and photophysical research into natural and nature‐inspired UV filter molecules is reviewed, with a focus on the application of these systems in next‐generation sunscreens. The results of time‐resolved UV spectroscopy experiments and theoretical studies are discussed.
Michael Hymas, Vasilios G. Stavros
wiley   +1 more source

Direct synthesis, characterization, in vitro and in silico studies of simple chalcones as potential antimicrobial and antileishmanial agents

Royal Society Open Science
Chalcone represents a vital biosynthetic scaffold owing to its numerous therapeutic effects. The present study was intended to synthesize 17 chalcone derivatives (3a–q) by direct coupling of substituted acetophenones and benzaldehyde.
Haroon ur Rashid, Sherwali Khan, Irum, Asad Khan, Nasir Ahmad, Tanzeel Shah, Khalid Khan   +6 more
doaj   +1 more source

Homoisoflavonoids—From Natural Specificity and Biosynthesis to Precision Health‐Promoting Mechanisms

Food Frontiers, Volume 7, Issue 3, May 2026.
Homoisoflavonoids are rare flavonoids with a unique bi‐aromatic oxygen‐heterocyclic structure. This review synthesizes their structure–activity relationships in anti‐inflammatory, hypoglycemic, and anticancer contexts. By highlighting their specific natural distribution and outlining biosynthetic pathways, it provides a conceptual framework and ...
Jing Zhang, Han Chen, Jinping Si, Zhigang Han, Xinfeng Zhang   +4 more
wiley   +1 more source

Comprehensive investigation on two-photon absorption enhancement via excited-state charge transfer in terminal modified chalcone derivatives

Results in Chemistry
Three chalcone derivatives with different terminal modifications (furan, biphenyl, pyrenyl) were designed and synthesized. The nonlinear optical (NLO) properties of chalcone derivatives were comprehensively analyzed by Z-scan, transient absorption ...
Linpo Yang, Jia Wei, Xueru Zhang, Yuxiao Wang, Minggen Zhao, Yinglin Song   +5 more
doaj   +1 more source

Transient [3,3] Cope rearrangement of 3,3-dicyano-1,5-dienes: computational analysis and 2-step synthesis of arylcycloheptanes. [PDF]

, 2018
A simple and modular route to arylcycloheptene scaffolds is reported. The two-step route from Knoevenagel adducts and allylic electrophiles is made possible through the design of a Cope rearrangement that utilizes a "traceless" activating group to ...
Fereyduni, Ehsan, Gonzalez, Gabriel, Grenning, Alexander J, Houk, KN, Sanders, Jacob N   +4 more
core   +1 more source

Effect of pH on recovery efficiency and anthocyanin composition of Clitoria ternatea extracts with application as lipid antioxidants in food preservation

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
pH significantly affects the extraction efficiency of TPC TAC and the extracted anthocyanin components. pH 3 and pH 7 yield the highest extraction efficiency and antioxidant activity. Extracts at pH 7 are suitable as blue color additives for neutral pH foods and as good antioxidants for fat‐containing gummies.
Kha Duyen Nguyen, Thi Thu Tra Tran, Ngọc Anh Le, Thi Anh Dao Dong   +3 more
wiley   +1 more source