Results 151 to 160 of about 48,655 (255)

Advances and opportunities for computational interrogation of plant proteins

The Plant Journal, Volume 126, Issue 3, May 2026.
SUMMARY Plants exhibit remarkable biochemical and physiological diversity, and are capable of adapting to a wide range of environmental conditions and stresses. This complexity makes them essential systems for understanding how life responds to a changing climate.
Sarah M. Bohling, Shaila Musharoff, Laura H. Gunn   +2 more
wiley   +1 more source

Design, Synthesis, and Evaluation of New Polyhydroxylated Bis‐Chalcones as Potential COX‐2 Selective Inhibitors

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Novel polyhydroxylated bis‐chalcones were successfully synthesized and demonstrated COX‐2 selective inhibition. The most potent and selective inhibitor exhibited a mixed‐type inhibition mechanism with COX‐2. Its additional bulk preferentially blocked the access to the active pocket of COX‐1 rather than COX‐2. Selective inhibition of COX‐2 is considered
Rui Pereira, Alberto N. Araújo, Daniela Ribeiro, Ismael Rufino, Nuno Martinho, Rita C. Guedes, Vera L. M. Silva, Eduarda Fernandes   +7 more
wiley   +1 more source

Effect of cinnamon supplementation on blood glucose and lipid levels in type2 diabetic patients [PDF]

This study was planned to investigate the effects of supplementation of cinnamon on fasting blood glucose levels and lipid profiles among type2 diabetic patients.
خادم حقیقیان, حسین, علی عسگرزاده, اکبر, فرساد نعیمی, علیرضا, نعمتی, علی, پورقاسم گرگری, بهرام   +4 more
core  

Chalcone-based Pyrazoline Derivatives as Modulators of Neuroinflammatory and Redox Pathways in Experimental Epilepsy. [PDF]

Mol Neurobiol
Delibaş EAÖ, Acungil ZK, Koç E, Özsoy Ş.   +3 more
europepmc   +1 more source

Structural, electronic and bioactive profiling of a 2'-hydroxychalcone-Ag composite: a DFT-supported biomedical study on anticancer, antioxidant and antibacterial activities. [PDF]

RSC Adv
Butt AL, Saira F, Ahmed S, Tahir S, Iqbal A, Siddiqa A, Mazhar K, Sohaila Naz S.   +7 more
europepmc   +1 more source

Cavitand-Mediated Photodimerization of Chalcones: The Effect of Supramolecular Influences and Temperature on Reaction Selectivity. [PDF]

Molecules
Chatterjee J, Pattabiraman M, Chakraborty D, Wysocki AL, Kovacs F.   +4 more
europepmc   +1 more source

Design, Synthesis, and Evaluation of Bis-Chalcones and Bis-Flavones as Selective COX-2 Inhibitors. [PDF]

Chem Biol Drug Des
Pereira R, Freitas M, Araújo AN, Silva VLM, Fernandes E.   +4 more
europepmc   +1 more source

Design, synthesis, and biological evaluation of novel chalcone derivatives: integrating molecular docking with <i>in vivo</i> anti-inflammatory and antinociceptive studies. [PDF]

RSC Adv
Shamim A, Nadeem H, Masaud SM, Hussain T, Bashir K, Alrokayan S, Haq IU, Latif M, Imran M, Irshad N.   +9 more
europepmc   +1 more source

Transition-Metal-Free One-Pot Synthesis of (Hetero)chalcones with Cysteine Protease Inhibitory Activity. [PDF]

ACS Omega
Arroio TR, Caires FJ, Almeida GO, Fernandes VHC, Pinto IWF, de Oliveira LVS, Vieira PC, Clososki GC.   +7 more
europepmc   +1 more source

Polyethylene Microplastics Inhibit Peanut Nodulation via Metabolic and Transcriptional Pathways. [PDF]

Plants (Basel)
Wu Y, Wu Z, Zheng Y, Yang J, Zhang J, Wang H, Yu T, Wu J, Li S.   +8 more
europepmc   +1 more source