Results 161 to 170 of about 33,682 (280)

Three privileged scaffolds, one pipeline: chalcones, pyrazolines and pyrazoles in drug discovery and fluorescent sensing. [PDF]

RSC Med Chem
Ciupa A.
europepmc   +1 more source

Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α‐Mangostin: A Structure–Activity Relationship Insight

ChemFoodChem, Volume 2, Issue 3, September 2026.
Free phenolic hydroxyl groups in the chemical structure of the natural xanthone α‐mangostin (MGT) contribute positively to achieving the anticancer profile against murine colon cancer, murine triple negative breast cancer, and human osteosarcoma cancer. ABSTRACT The α‐mangostin (MGT) is a natural xanthone obtained from the pericarp of mangosteen fruit (
Otávio Augusto Chaves, Afonso Santine M. M. Velez, Lívia Stenico, Douglas Chaves de Alcântara Pinto, Debora Decote‐Ricardo, Eliezer Avila Gandra, Marco Edilson Freire de Lima, Carlos Serpa   +7 more
wiley   +1 more source

Endothelial cell biomechanical adaptation to altered connexin 43 expression under fluid shear stress. [PDF]

J Cell Sci
Islam MM, Subramanianbalachandar V, Steward R.   +2 more
europepmc   +1 more source

Effects of high‐moisture extrusion processing on reducing anti‐nutritional factors and allergenicity in plant‐based materials—A mini review

Food Biomacromolecules, Volume 3, Issue 3, Page 424-434, September 2026.
Abstract The rising demand for plant‐based meat alternatives has had advancements in processing technologies such as extrusion to meet consumer preferences for enhanced sensory qualities and nutritional benefits. High moisture extrusion (HME), a thermo‐mechanical process employing elevated moisture levels (40%–70%), has emerged as a promising method ...
Nur Hameedah Binte Ramadhan, Yuzhu Mao, Juan Du   +2 more
wiley   +1 more source

Structural Dynamics and Susceptibility of Aminonaphthoquinone-Chalcone Hybrids Against Human Tyrosinase. [PDF]

Int J Mol Sci
Sabuakham S, Nuramrum N, Rungrotmongkol T, Pingaew R, Mahalapbutr P.   +4 more
europepmc   +1 more source

Advances in protein–polyphenol complexation: Unraveling mechanisms, modulation, and functional outcomes

Food Biomacromolecules, Volume 3, Issue 3, Page 515-531, September 2026.
Abstract Polyphenolic compounds have attracted increasing market demand and extensive attention due to their potential health benefits and bioactivities. Meanwhile, proteins are widely used in the food industry for their nutritional and functional properties. However, the application of proteins in the food industry is often limited by challenges, such
Fang Li, Ziming Xu, Tian Zhao, Gongshuai Song, Danli Wang, Tinglan Yuan, Ling Li, Jinyan Gong   +7 more
wiley   +1 more source

Retraction Note: Design, synthesis and biological evaluation of novel chalcone-derived thioxopyridine and pyrazolopyridine compounds as antimicrobial agents. [PDF]

Sci Rep
Algaber G, Shyamala P, Dammag Z, Al-Haddad M.   +3 more
europepmc   +1 more source

Molecular Mechanisms and Regulation of Anthocyanin Biosynthesis in Rosaceae Fruits: A Review

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Five‐tiered regulatory network governing anthocyanin biosynthesis in Rosaceae fruits, integrating environmental signals, epigenetic/transcriptional control, flavonoid metabolism, pigment trafficking and breeding translation. This review elaborates layered regulatory networks underlying anthocyanin production in core Rosaceae crops (Malus, Pyrus ...
Menghua Luo, Wanjia Tang, Xiaoqing Yuan, Can Hu   +3 more
wiley   +1 more source

Integrative multi-omics analysis prioritizes compartment-specific candidate targets of gut microbiota metabolites in diabetic kidney disease. [PDF]

Front Immunol
Xie F, He X, Chen W, Li J, Lin S, Bao Q, Li W, Cheng J, Ma Y, Wu Z, Li H.   +10 more
europepmc   +1 more source

Coix Seed Attenuates Acute Lung Injury via NLRP3 Signaling Pathway: Efficacy, Active Components, and Mechanisms

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
From component identification to target validation: Coix seed extract exerts a protective effect against acute lung injury (ALI) by synergistically inhibiting inflammatory cytokines and NLRP3‐mediated pyroptosis through multiple signaling pathways. ABSTRACT Coix seed is a medicinal and nutritional resource, but its protective effects against acute lung
Qi Yan, Yuyan Li, Tingyan Chen, Wenjing Liu, Youshuo Dong, Zhangbo Ao, Hongmei Wu, Feng Xu   +7 more
wiley   +1 more source