Chalcone suppresses tumor growth through NOX4-IRE1α sulfonation-RIDD-miR-23b axis
Chalcone is a polyphenolic compound found abundantly in natural plant components. They have been acclaimed as potential antitumor compounds in multiple tumor cells. However, not much attention has been paid to elucidate its antitumor mechanism of action.
Hyun-Kyoung Kim+8 more
doaj
Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa. [PDF]
RNA isolated from the glands of a Delta(9)-tetrahydrocannabinolic acid (THCA)-producing strain of Cannabis sativa was used to generate a cDNA library containing over 100 000 expressed sequence tags (ESTs).
Dixon, Richard A+8 more
core
The first example of molecular docking of the SARS-CoV-2 main protease for COVID-19 [Mpro, Protein Data Bank (PDB) code 7BQY] by a chalcone-based ligand, namely, (E)-1-(2,4-dichlorophenyl)-3-[4-(morpholin-4-yl)phenyl]prop-2-en-1-one, C19H17Cl2NO2, I, is ...
M. A. Alsafi, D. Hughes, M. Said
semanticscholar +1 more source
Evaluation of direct pulp capping with a synthetic chalcone: a preliminary histological study.
The aim of this study is to evaluate the action of the synthetic chalcone 1-phenyl-3-(4-chlorophenyl)-2-propen-1-one to induce pulp healing in rats.
David Tames+6 more
doaj +1 more source
Plastid redox state and sugars: Interactive regulators of nuclear-encoded photosynthetic gene expression [PDF]
Feedback regulation of photosynthesis by carbon metabolites has long been recognized, but the underlying cellular mechanisms that control this process remain unclear.
Dominy, P J+3 more
core +2 more sources
Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin
Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable.
Bing Zhang+9 more
doaj +1 more source
A basic helix-loop-helix transcription factor, PhFBH4, regulates flower senescence by modulating ethylene biosynthesis pathway in petunia. [PDF]
The basic helix-loop-helix (bHLH) transcription factors (TFs) play important roles in regulating multiple biological processes in plants. However, there are few reports about the function of bHLHs in flower senescence.
Bui, Mai+5 more
core +1 more source
Isoliquiritigenin, a Strong nod Gene- and Glyceollin Resistance- Inducing Flavonoid from Soybean Root Exudate [PDF]
Isoflavonoid signal molecules from soybean (Glycine max (L.) Merr.) seed and root exudate induce the transcription of nodulation (nod) genes in Bradyrhizobium japonicum. In this study, a new compound with symbiotic activity was isolated from soybean root
Brandt, Sebastian+3 more
core
Anthocyanin absorption and metabolism by human intestinal Caco-2 cells: a review [PDF]
Anthocyanins from different plant sources have been shown to possess health beneficial effects against a number of chronic diseases. To obtain any influence in a specific tissue or organ, these bioactive compounds must be bioavailable, i.e., effectively ...
Battino, Maurizioeditor+4 more
core +3 more sources
Multiple roles for UV RESISTANCE LOCUS8 in regulating gene expression and metabolite accumulation in arabidopsis under solar ultraviolet radiation [PDF]
Photomorphogenic responses triggered by low fluence rates of ultraviolet B radiation (UV-B; 280–315 nm) are mediated by the UV-B photoreceptor UV RESISTANCE LOCUS8 (UVR8).
Aphalo, P.J.+9 more
core +1 more source