Results 241 to 250 of about 74,636 (287)

Heteroatom-Synergistic Effect on Anchoring Polysulfides In Chalcone-Linked Nanographene Covalent Organic Frameworks for High-Performance Li─S Batteries. [PDF]

open access: yesAdv Sci (Weinh)
Ranjeesh KC   +9 more
europepmc   +1 more source
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Chalcone hybrids and their antimalarial activity

Archiv der Pharmazie, 2020
Malaria, one of the most striking, re‐emerging infectious diseases caused by the genus Plasmodium, places a huge burden on global healthcare systems. A major challenge in the control and eradication of malaria is the continuous emergence of increasingly ...
P. Cheng   +4 more
semanticscholar   +4 more sources

Design, Synthesis, and Antifungal Activity of Novel Chalcone Derivatives Containing a Piperazine Fragment.

Journal of Agricultural and Food Chemistry, 2022
In an attempt to find the biorational pesticides, 20 novel chalcone derivatives containing a piperazine fragment were designed and synthesized. Their fungicidal activities and preliminarily action mechanism against Rhizoctonia solani were evaluated ...
Qing Zhou   +8 more
semanticscholar   +1 more source

ChemInform Abstract: Bioactivities of Chalcones

ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Michael A. Beazely   +3 more
openaire   +3 more sources

Structure of a chalcone

Acta Crystallographica Section C Crystal Structure Communications, 1993
1-(7-Hydroxy-2,2-dimethylchroman-6-yl)-3-phenyl-2-propen-1-one, C 20 H 20 O 3 , M r =308.38, P2 1 /a, a=12.002 (2), b=11.013 (2), c=12.652 (3) A, β=106.24 (3) o , V=1605.6 A 3 , Z=4, D m =1.26 (2), D x =1.275 Mg m -3 , λ(Mo Kα)=0.71069 A, μ=0.079 mm -1 , F(000)=656, T=293 K, R=0.037, wR=0.034 for 892 reflections with I>3σ(I).
ALEX, G   +5 more
openaire   +3 more sources

Modulation of Apoptosis and Epithelial-Mesenchymal Transition E-cadherin/TGF-β/Snail/TWIST Pathways by a New Ciprofloxacin Chalcone in Breast Cancer Cells

Anticancer Research, 2021
Background/Aim: This study aimed to investigate the effect of the new ciprofloxacin chalcone [7-(4-(N-substituted carbamoyl methyl) piperazin-1 yl)] on the proliferation, migration, and metastasis of MCF-7 and MDA-MB-231 breast cancer cell lines ...
Rania Alaaeldin   +3 more
semanticscholar   +1 more source

Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure-activity relationship.

Medicinal research reviews (Print), 2020
The continuous emergency of drug-resistant cancers and the low specificity of anticancer agents have been the major challenges in the control and treatment of cancer, making an urgent need to develop novel anticancer agents with high efficacy. Chalcones,
F. Gao, Gang Huang, Jiaqi Xiao
semanticscholar   +1 more source

Stereoselectivity of chalcone isomerase with chalcone derivatives: a computational study

Journal of Molecular Modeling, 2013
Chalcone isomerase (CHI) catalyzes the intramolecular cyclization of chalcones into flavonoids. The activity of CHI is essential for the biosynthesis of flavonoids precursors of floral pigments and phenylpropanoid plant defense compounds. In the present study, we explored the detailed binding structures and binding free energies for two different ...
Yuan Yao   +3 more
openaire   +3 more sources

The Quinazoline-Chalcone and Quinazolinone-Chalcone Hybrids: A Promising Combination for Biological Activity

Mini-Reviews in Medicinal Chemistry, 2021
Quinazoline and/or chalcones derivatives are important targets in several areas of chemical sciences, mainly, in the medicinal chemistry and pharmaceutical research. The purpose of this review was to systematize the information available in the literature, including patents, regarding the benefits, exerted by the combination of these two ...
Dennis Russowsky   +2 more
openaire   +2 more sources

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