Results 131 to 140 of about 22,032 (252)

Novel Al(OH)3 and Ti/Fe@Al(OH)3 nano catalyzed of N-(3-((E)-3-(4-Adamant-1-yl)-phenyl) acryloyl) phenyl) quinoline-2-carboxamide Synthesis and its Molecular Docking, Quantum chemical Studies

Chemical Physics Impact
Using a green chemical Al(OH)3 and Ti/Fe@Al(OH)3 nanocatalyzed method, a number of new adamantyl substituted quinoline based chalcone derivative 1 to chalcone derivative 4 (CD1 to CD4) have been synthesized.
C. Thirumurugan, R. Thirumalaisamy, A. Lalitha, P. Vadivel, R․Selva Kumar, Kalandar Ameer, Ramalingam Karthik Raja, Shyam Kumar Rajaram, Ponmurugan Karuppiah   +8 more
doaj   +1 more source

Chalcone Derivatives: Synthesis and Cytotoxicity Assays

Al-Nahrain Journal of Science
The research included the formation of chalcone derivatives, which are organic materials with biological importance, on which this research is based. The Chalcone derivatives were synthesised from the Claisen-Schmidt condensation reaction.
Asraa H. Ahmed, Ahmed Ahmed, Haikel Jelassi   +2 more
openaire   +1 more source

CHALCONES: THE PROMISING COMPOUNDS TO PROVIDE NEW WAYS FOR CANCER TREATMENT [PDF]

, 2014
Chalcones (1,3-diphenylpropen-1-ones), a biosynthetic product of the shikimate pathway, belonging to flavanoid family are precursors of open chain flavonoids and isoflavonoids, which are abundant in edible plants.
Retno, Arianingrum
core  

Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience

New Phytologist, Volume 250, Issue 2, Page 762-787, April 2026.
Summary B‐box (BBX) proteins were initially characterized as transcription factors connecting light signaling to the regulation of flowering time and seedling photomorphogenesis. However, over the last decade, increasing evidence has shown that they integrate light and hormone signaling, modulating multiple physiological processes during plant life. In
Bruno Silvestre Lira, Juliene Moreira, Luciano Freschi, Magdalena Rossi   +3 more
wiley   +1 more source

Cobalt‐Salen Catalysed Hydration of Alkenes With Water: A Complementary Ionic Approach to the Mukaiyama Hydration

Advanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.
A cobalt‐salen catalysed hydration of olefins with water is reported, resulting in Markovnikov alcohol products. The reaction proceeds rapidly under mild conditions and exhibits excellent functional group tolerance, supporting a wide range of styrenyl and non‐activated alkenes.
David G. Groves, Reece H. Hoogesteger, Balakumar Emayavaramban, Craig P. Johnston   +3 more
wiley   +1 more source

Design, Synthesis, Characterization and in vivo Antidiabetic Activity Evaluation of Some Chalcone Derivatives

Drug Design, Development and Therapy, 2021
Semere Welday Kahssay,1 Gebremedhin Solomon Hailu,2 Kebede Taye Desta3 1Mizan-Tepi University, College of Health Sciences, School of Pharmacy, Department of Pharmaceutical Chemistry, Mizan-Aman, Ethiopia; 2Mekelle University, College of Health Sciences ...
Welday Kahssay S, Hailu GS, Taye Desta K
doaj  

Synthesis of Some Novel Chalcone and 3,5‐Disubstituted Pyrazoline Derivatives: Evaluation of Their α‐Amylase and α‐Glucosidase Inhibitory Activities In Vitro and In Silico

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
A novel pyrazoline derivative (P2) was synthesized and demonstrated potent α‐glucosidase inhibition (IC50 = 2.10 µM), significantly surpassing acarbose and highlighting its promise as an effective oral antidiabetic agent. ABSTRACT This study reports the synthesis of some novel chalcone (C1–C3) and 3,5‐disubstituted pyrazoline derivatives (P1–P3 ...
Fatma Erbay, Melike Yildirim Akatin, Fatma Demir, Nuran Kahriman, Ahmet Colak, Nagihan Saglam Ertunga, Murat Küçük   +6 more
wiley   +1 more source

Synthesis, characterization, biological screening and in silico studies of novel pyrazole-chalcone derivatives as potent aromatase inhibitors for breast cancer therapy

Future Journal of Pharmaceutical Sciences
Background Chalcone derivatives, which are known for their non-steroidal anticancer properties, have been extensively studied. One potential application of chalcone is as aromatase inhibitors, a crucial strategy for treating estrogen receptor-positive ...
Ishvarchandra Parmar, Samir Patel, Umang Shah, Chirag Patel, Alkesh Patel, Arya Patel   +5 more
doaj   +1 more source

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, Volume 12, Issue 1, Page 1-15, March 2026.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

Resolution of a Chiral β‐Aminoketone via Diastereomeric Salt Formation: From Experimental Evidence to Molecular‐Level Insights Into Solution‐Phase Clusters

Chirality, Volume 38, Issue 3, March 2026.
Subtle but significant differences between the heterochiral and homochiral salts during the prenucleation stage, revealed by molecular simulations, are related to the enantiomeric separation of a β‐aminoketone through the precipitation of its corresponding diastereomeric salts. ABSTRACT The classical diastereomeric salt resolution approach was employed
Caterina Momoli, Laura Palombi, Isabella Daidone, Erica Scarel, Massimiliano Aschi   +4 more
wiley   +1 more source