Results 141 to 150 of about 3,527,028 (317)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Solar Challenge

open access: yes, 1996
A Solar Car on the road, 1996 World Solar Challenge, Stuart Highway, Coomalie Creek, NT, 27 October 1996 ...

core  

The AudioLabs System for the Blizzard Challenge 2023

open access: yes
6368In this paper, we describe our contribution to the Blizzard Challenge 2023. This challenge has the goal of understanding and comparing research techniques in building corpus-based speech synthesizers on the same data.
Zalkow, Frank   +7 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Challenge To The South

open access: yes, 1992
22cm ...
Challenge
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Challenge reception

open access: yes, 1996
People attending the 1996 World Solar Challenge reception, The Great Hall, Parliament House, Darwin, NT, 26 October 1996 ...

core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Challenge Car

open access: yes, 1996
One of the solar cars crossing Coomalie Creek, 1996 World Solar Challenge, Stuart Highway, Coomalie Creek, NT, 27 October 1996 ...

core  

The Blizzard Challenge 2008 [PDF]

open access: yes, 2008
The Blizzard Challenge 2008 was the fourth annual Blizzard Challenge. This year, participants were asked to build two voices from a UK English corpus and one voice from a Man- darin Chinese corpus.
King, S.; id_orcid   +7 more
core  

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