Results 71 to 80 of about 1,915,229 (296)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Paranoid Transformer: Reading Narrative of Madness as Computational Approach to Creativity

Future Internet, 2020
This paper revisits the receptive theory in the context of computational creativity. It presents a case study of a Paranoid Transformer—a fully autonomous text generation engine with raw output that could be read as the narrative of a mad digital persona
Yana Agafonova, Alexey Tikhonov, Ivan P. Yamshchikov   +2 more
doaj   +1 more source

Probability Guide to Gambling: The Mathematics of Dice, Slots, Roulette, Baccarat, Blackjack, Poker, Lottery and Sport Bets [PDF]

, 2006
Over the past two decades, gamblers have begun taking mathematics into account more seriously than ever before. While probability theory is the only rigorous theory modeling the uncertainty, even though in idealized conditions, numerical probabilities ...
Barboianu, Catalin
core  

Theoretical Analysis of Acceptance Rates in Multigrid Monte Carlo

, 1991
We analyze the kinematics of multigrid Monte Carlo algorithms by investigating acceptance rates for nonlocal Metropolis updates. With the help of a simple criterion we can decide whether or not a multigrid algorithm will have a chance to overcome critial
A. Hulsebos, G. Mack, G. Mack, G. Mack, G. Parisi, J. Goodman, J. Goodman, J. Goodman, Klaus Pinn, M. Hasenbusch, M. Hasenbusch, M. Hasenbusch, M. L. Laursen, Martin Grabenstein, R. G. Edwards, R. H. Swendsen, S. Gupta, T. Kalkreuter, U. Wolff, U. Wolff   +19 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Can a Divinely Guided World Include Blind Chance?

Zygon
Compatibilism, or accommodationism, is the view that evolutionary theory and interventionist theism are compatible. According to compatibilists, God can guide the biosphere while allowing for chance events.
M. Ebrahim Maghsoudi, Seyed Hassan Hosseini   +1 more
doaj   +2 more sources

Light incoherence due to quantum-gravitational fluctuations of the background space

, 2009
Based on the theory of mutual coherence of light from an extended incoherent quasi-monochromatic source (providing a basis of stellar interferometry) we estimate the degree of light incoherence due to quantum-gravitational fluctuations of the background ...
Adler, Ahluwalia, Alden Mead, Alden Mead, Amati, Amelino-Camelia, Amelino-Camelia, Ashtekar, Bekenstein, Bekenstein, Born, Bousso, Bousso, Bousso, Christiansen, Coule, Doplicher, Flanagan, Garay, Gross, Guida, Hopkins, Hopkins, Jack Ng, Janossy, Janossy, Konishi, Károlyházy, Károlyházy, Károlyházy, Li, Lieu, Maggiore, Maggiore, Maggiore, Maziashvili, Maziashvili, Michael Maziashvili, Ng, Padmanabhan, Ragazzoni, Rovelli, Sasakura, Scardigli, Seiberg, Steinbring, Thiemann, van Cittert, van Cittert, Veneziano, Yoneya, Yoneya, Zernike   +52 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Prospect theory-based formulation of chance constrained portfolio optimization problem using loan

SICE Journal of Control, Measurement, and System Integration
Portfolio optimization that allows the borrowed money from a loan to be invested in risk assets has been formulated as a chance constrained problem. In this paper, in order to reflect investor preferences called “values” in the solution, or the portfolio,
Kiyoharu Tagawa, Yukiko Orito
doaj   +1 more source

«Theory of everything»: types of information and the theory of interpretation in «Philosophy of chance» by Stanisław Lem

Семиотические исследования
The article is focused on the S. Lem’s perspective of the literary work as a product of the reader’s apprehension of the text in the culture discourse. The aim of the research is to describe the Lem’s view on the structure of the text; Lem’s encounter as
Ekaterina A. A. Smerdowa
doaj   +1 more source