Results 71 to 80 of about 4,355,565 (259)

Compact Four-Channel Optical Emission Module with High Gain

open access: yesPhotonics
In this paper, a four-channel optical emission module is developed using hybrid integration technology that integrates directly modulated laser (DML) chips, low-noise amplifier (LNA) chips, and control circuits, with dimensions of 24.4 mm × 21 mm × 5.9 ...
Xiying Dang   +6 more
doaj   +1 more source

Effect of microfluidic channel integration onto gold microelectrode on its redox electrochemistry. [PDF]

open access: yesTurk J Chem, 2023
Uçar A   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Institute on Community Integration Annual Report: 2014-15

open access: yes, 2016
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Center for Excellence in Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Development of Self‐Aligned Top‐Gate Transistor Arrays on Wafer‐Scale Two‐Dimensional Semiconductor

open access: yesAdvanced Science
Two‐dimensional semiconductor materials (2DSM) effectively mitigate the short‐channel effect due to their atomic thickness, offering significant advantages over traditional silicon‐based materials, particularly in short channel length.
Yuxuan Zhu   +26 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Channel 40 news segment on E. Coli rapid detection method (April 1998)

open access: yes, 1998
This is a short Channel 40 news segment on Dr. Chun-Kwun Wun and Dr. Frank J. Torre development of a E. Coli Rapid Detection method. The segment is about two minutes and 20 seconds long. The segment was digitized from a VHS tape which over the years seem
ABC Channel 40;
core  

Electronic control of H+ current in a bioprotonic device with Gramicidin A and Alamethicin

open access: yesNature Communications, 2016
Conventional electronics use electrons as charge carriers whereas biological systems use ions, confounding integration of electronics with biology. Here the authors show voltage-regulated flow of protons across a supported lipid bilayer using the ion ...
Zahra Hemmatian   +7 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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