Results 61 to 70 of about 180,260 (215)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
IEEE Access, 2019 This paper focuses on the analysis of propagation characteristics for train-ground communication (TGC) systems in tunnel scenarios at both low frequency and millimeter-wave (mmWave) bands, based on ray-tracing (RT) simulation.
Tao Zhou +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Attention-Guided Wireless Channel Modeling and Generating
Applied SciencesDue to the fast advancement in wireless communication technology, the demand for the modeling and generating of wireless channels is increasing. Deep learning technology is gradually applied in the wireless communication field, and the Generative ...
Yawen He, Nan Xu, Li Cheng, Haiwen Yuan
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A Universal Attenuation Model of Terahertz Wave in Space-Air-Ground Channel Medium
IEEE Open Journal of the Communications SocietyProviding continuous bandwidth over several tens of GHz, the Terahertz (THz) band (0.1-10 THz) supports space-air-ground integrated network (SAGIN) in 6G and beyond wireless networks.
Zhirong Yang, Weijun Gao, Chong Han
doaj +1 more source
Cooperative In-Vivo Nano-Network Communication at Terahertz Frequencies
IEEE Access, 2017 Nano-devices have great potential to play a vital role in future medical diagnostics and treatment technologies because of its non-invasive nature and ability to reach delicate body sites easily as compared with conventional devices.
Qammer H. Abbasi +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source