Results 111 to 120 of about 11,955 (223)

Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery, Jacob A. Miller, Steven Poelzing, Seth H. Weinberg   +3 more
wiley   +1 more source

Channelopathies of the nervous and musculoskeletal system [PDF]

, 2012
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate: Bc. Monika Šrámková Supervisor: Doc. MUDr. Josef Herink, DrSc.
Šrámková, Monika
core  

Channels and channelopathies [PDF]

Acta Physiologica, 2016
P B, Persson, A, Bondke Persson
openaire   +2 more sources

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source

Time‐Efficient Interleaved Spin Density‐Weighted and Inversion Recovery 23Na MRI of the Human Calf Muscle at 7 T

Magnetic Resonance in Medicine, Volume 96, Issue 6, Page 2675-2684, December 2026.
ABSTRACT Purpose Spin density‐weighted (SDW) and inversion recovery (IR) 23Na MRI provide different sodium contrasts with complementary information. Therefore, the aim was to develop a time‐efficient sequence scheme capable of providing both contrasts by acquiring SDW and IR 23Na MRI data within a single sequence without additional measurement time ...
Tobias Wilferth, Fiona Meyer, Jordan M. Höhn, Michael Uder, Armin M. Nagel   +4 more
wiley   +1 more source

Editorial: Channel Modulation in Neurodegeneration and Neuroprotection

Frontiers in Pharmacology, 2022
Jacques Joubert, Sarel F. Malan, Werner J. Geldenhuys   +2 more
doaj   +1 more source

Epileptic channelopathies

, 2003
RESUMEN: Se hace una revisión actualizada sobre las epilepsias debidas a alteraciones de los diferentes canales iónicos, con énfasis en su presentación clínica y genotipificación.
Cornejo Ochoa, José William, Carrizosa Moog, Jaime   +1 more
core  

Intracardiac electrophysiology to characterize susceptibility to ventricular arrhythmias in murine models

Frontiers in Physiology
Introduction: Sudden cardiac death (SCD) and ventricular fibrillation are rare but severe complications of many cardiovascular diseases and represent a major health issue worldwide. Although the primary causes are often acute or chronic coronary diseases,
Marine C. Ferrand, Gauthier Giordano, Gauthier Giordano, Nathalie Mougenot, Pierre-Léo Laporte, Pierre-Léo Laporte, Nicolas Vignier, Arnaud Leclerc, Vincent Algalarrondo, Fabrice Extramiana, Fabrice Extramiana, Flavien Charpentier, Nathalie Neyroud   +12 more
doaj   +1 more source

Epicardial adipose tissue‐linked leukotriene and cytokine signalling pathways – novel targets for prevention of obesity‐ and diabetes‐linked ventricular arrhythmia

The Journal of Physiology, EarlyView.
Kelly A. Aromolaran, Ademuyiwa S. Aromolaran   +1 more
wiley   +1 more source

Editorial: Cardiac Pacemaking in Health and Disease: From Genes to Function

Frontiers in Physiology, 2022
Alicia D’Souza, Gerard J. J. Boink, Gerard J. J. Boink, Futoshi Toyoda, Pietro Mesirca, Pietro Mesirca   +5 more
doaj   +1 more source