SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source
Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1) [PDF]
Berry, Kayla N +4 more
core +2 more sources
Editorial: New Insights in Skeletal Muscle Channelopathies - A Rapidly Expanding Field
Lorenzo Maggi +3 more
doaj +1 more source
The Bioelectricity Revolution: A Discussion Among the Founding Associate Editors. [PDF]
Adams, Dany Spencer +8 more
core +1 more source
Editorial: Ion channels in the nervous system. [PDF]
Urrutia J, Villarroel A, Revuelta M.
europepmc +1 more source
Channelopathies in Cav1.1, Cav1.3, and Cav1.4 voltage-gated L-type Ca2+ channels [PDF]
Jörg Striessnig +2 more
core +1 more source
Alternative splicing in voltage-gated sodium channels: mechanisms, regulatory networks and therapeutic implications. [PDF]
Qiu J +6 more
europepmc +1 more source
Further mystification of SCN5A phenotypes: sodium channel blockade in individuals with loss-of-function sodium channel mutations dangerous or helpful? [PDF]
Postema PG.
europepmc +1 more source
Canalopatías en la epilepsia idiopática monogénica en perros [PDF]
Epilepsy is a common neurological disorder both dogs and humans. Nevertheless, unlike occurs in humans, in dogs it is a badly characterized disease. In humans, it is known from some time ago, that some idiopathic epilepsies present patterns of mendelian ...
Gilabert Santos, J.A. +2 more
core +1 more source

