Results 91 to 100 of about 8,166 (199)

Alternative Lead ECG Placements

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
Alternative ECG lead placements can improve diagnostic yield when the standard 12‐lead ECG is suboptimal or infeasible. This review summarizes practical, scenario‐driven modifications (right‐sided, posterior, seated/prone, Lewis, Fontaine, torso‐based, and monitoring configurations) to better detect ischemia, right ventricular disease/ARVD, and ...
José Luis Morales‐Arteaga   +12 more
wiley   +1 more source

Stabilizing Extreme Few‐Shot ECG Classification via Self‐Supervised Contrastive Pretraining

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
Under extreme few‐shot ECG classification, supervised training frequently collapses to degenerate solutions. Self‐supervised pretraining stabilizes optimization, eliminates early collapse, and enables reproducible multi‐class rhythm classification with limited labeled data. ABSTRACT In clinical electrocardiogram (ECG) analysis, high‐quality annotations
LiuPing Zeng   +3 more
wiley   +1 more source

Population‐Based Study Found Low Risk of Misdiagnosing Long QT Syndrome as Breath‐Holding Spells in Swedish Children

open access: yesActa Paediatrica, Volume 115, Issue 5, Page 1116-1125, May 2026.
ABSTRACT Aim An electrocardiogram is commonly recommended in breath‐holding spell management, mainly to rule out long QT syndrome. This retrospective study investigated the risk of long QT syndrome being misdiagnosed as breath‐holding spells in a paediatric population in southern Sweden.
Sanna Hellström Schmidt   +3 more
wiley   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1845-1859, May 2026.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim   +10 more
wiley   +1 more source

Electrocardiogram May Fail to Identify Proportion of High-Risk Individuals: Analysis of Series of 50 Sudden Death Cases

open access: yesCardiogenetics
Background: An electrocardiogram (ECG) is an essential and easily available diagnostic test in the management of cardiomyopathies and channelopathies. Different strategies based on ECG have been recommended for general population and athlete screening ...
Mariela Salar-Alcaraz   +10 more
doaj   +1 more source

Opening closed inward rectifier potassium channel doors

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2197-2218, May 2026.
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger   +3 more
wiley   +1 more source

Multiple Regulatory Signals and Components in the Modulation of Bicarbonate Transporters

open access: yesPharmaceutics
Bicarbonate transporters are responsible for the appropriate flux of bicarbonate across the plasma membrane to perform various fundamental cellular functions.
Hyeong Jae Kim, Jeong Hee Hong
doaj   +1 more source

SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley   +1 more source

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