Results 231 to 240 of about 17,118 (247)
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Conformational Changes of Channelrhodopsin-2
Journal of the American Chemical Society, 2009Channelrhodopsin-2 (ChR2) is a member of the new class of light-gated ion channels which serve as phototaxis receptors in the green alga Chlamydomonas reinhardtii. The protein is employed in optogenetics where neural circuits are optically stimulated under high spatiotemporal control.
Radu, Ionela +5 more
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Enhancing Channelrhodopsins: An Overview
2016After the discovery of Channelrhodopsin, a light-gated ion channel, only a few people saw the diverse range of applications for such a protein. Now, more than 10 years later Channelrhodopsins have become widely accepted as the ultimate tool to control the membrane potential of excitable cells via illumination.
Jonas, Wietek, Matthias, Prigge
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Exciton Circular Dichroism in Channelrhodopsin
The Journal of Physical Chemistry B, 2014Channelrhodopsins (ChRs) are of great interest currently because of their important applications in optogenetics, the photostimulation of neurons. The absorption and circular dichroism (CD) spectra of C1C2, a chimera of ChR1 and ChR2 of Chlamydomonas reinhardtii, have been studied experimentally and theoretically.
PESCITELLI, GENNARO +6 more
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Structure–Function Relationship of Channelrhodopsins
2021Ion-translocating rhodopsins, especially channelrhodopsins (ChRs), have attracted broad attention as a powerful tool to modulate the membrane potential of cells with light (optogenetics). Because of recent biophysical, spectroscopic, and computational studies, including the structural determination of cation and anion ChRs, our understanding of the ...
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Optogenetic control of medaka behavior with channelrhodopsin
Development, Growth & Differentiation, 2023AbstractOptogenetics enables the manipulation of neural activity with high spatiotemporal resolution in genetically defined neurons. The method is widely used in various model animals in the neuroscience and physiology fields. Channelrhodopsins are robust tools for optogenetic manipulation, but they have not yet been used for studies in medaka.
Takahide Seki +2 more
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Channelrhodopsins: directly light-gated cation channels
Biochemical Society Transactions, 2005Phototaxis and photophobic responses of green algae are mediated by rhodopsins with microbial type chromophores, i.e. all-trans-retinal in the ground state. The green alga Chlamydomonas reinhardtii was recently completely sequenced and the EST (expressed sequence tag) database was made public.
Nagel, G. +5 more
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Channelrhodopsin reveals its dark secrets
Science, 2017A high-resolution structure of channelrhodopsin 2 provides key insights for ...
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Evolution of the Channelrhodopsin Photocycle Model
ChemPhysChem, 2010AbstractMany processes in green algae are under control of rhodopsin‐type photoreceptors, but only a few have been studied at least in some detail in the past. Up to now, functionally and biochemically only the channelrhodpsins ChR1 and ChR2 are characterized.
Katja, Stehfest, Peter, Hegemann
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Progress in brain research, 2012
Classically, temporally precise excitation of membrane potential in neurons within intact tissue can be achieved by direct electrical stimulation or indirect electrical stimulation induced by changing magnetic fields. Both of these approaches have a predetermined selectivity based on the biophysical properties of the nervous tissue and membrane in the ...
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Classically, temporally precise excitation of membrane potential in neurons within intact tissue can be achieved by direct electrical stimulation or indirect electrical stimulation induced by changing magnetic fields. Both of these approaches have a predetermined selectivity based on the biophysical properties of the nervous tissue and membrane in the ...
openaire +2 more sources