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Structure-Functional Analysis of Channelrhodopsins
2015Channelrhodopsin (ChR) was the first light-gated cation channel to be discovered from green algae. Since the inward flow of cations triggers neuron firing, neurons expressing ChRs can be optically controlled, even within freely moving mammals. Although ChR has been broadly applied to neuroscience research, little is known about its molecular mechanisms.
Hideaki E. Kato +2 more
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Molecular Dynamics Simulations of Channelrhodopsin Chimera, C1C2
2020Molecular dynamics (MD) simulations have been successfully used for modeling dynamic behavior of biologically relevant systems, such as ion channels in representative environments to decode protein structure-function relationships. Protocol presented here describes steps for generating input files and modeling a monomer of transmembrane cation channel,
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Spike engineering with Channelrhodopsin-2
Neuroscience Letters, 2011Nir Grossman +2 more
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Molecular determinant differenciating Chlamydomonas channelrhodopsins
Neuroscience Research, 2009Hongxia Wang +7 more
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