Processes underlying the nutritional programming of embryonic development by iron deficiency in the rat [PDF]
, 2012 Peer reviewedPublisher ...
Gambling, Lorraine +5 more
core +6 more sources
Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics
Frontiers in Molecular Biosciences, 2018 The 60 kDa heat shock protein (Hsp60) is classically known as a mitochondrial chaperonin protein working together with co-chaperonin 10 kDa heat shock protein (Hsp10).
Qianli Meng +2 more
doaj +1 more source
Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space [PDF]
, 1992 Cytochrome b2 reaches the intermembrane space of mitochondria by transport into the matrix followed by export across the inner membrane. While in the matrix, the protein interacts with hsp60, which arrests its folding prior to export.
Guiard, Bernard +6 more
core +1 more source
Formation of the chaperonin complex studied by 2D NMR spectroscopy. [PDF]
PLoS ONE, 2017 We studied the interaction between GroES and a single-ring mutant (SR1) of GroEL by the NMR titration of 15N-labeled GroES with SR1 at three different temperatures (20, 25 and 30°C) in the presence of 3 mM ADP in 100 mM KCl and 10 mM MgCl2 at pH 7.5.
Toshio Takenaka +10 more
doaj +1 more source
Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness [PDF]
, 2016 Trypanosoma brucei are protozoan parasites that cause African sleeping sickness in humans (also known as Human African Trypanosomiasis—HAT). Without treatment, T. brucei infections are fatal.
Abdeen, Sanofar +9 more
core +1 more source
Sakarya Tıp Dergisi, 2013 İmmunosupresif özelliğe sahip bir protein olan erken gebelik faktörü (EGF) fertilizasyondan sonra yaklaşık 6-24 saat içerisinde maternal serumda tespit edilebilir ve pek çok canlı türünde gebeliğin ilk iki trimesteri boyunca üretilir.
Elvan Özbek +2 more
doaj +1 more source
GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus
Diagnostics, 2022 A point-of-care diagnostic for early and rapid diagnosis of scrub typhus caused by Orientia tsutsugamushi is required for prompt and proper treatment of patients presenting with undifferentiated febrile illnesses.
Nitaya Indrawattana +7 more
doaj +1 more source
Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy [PDF]
, 2019 The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins.
Cappello F. +4 more
core +1 more source
Metabolomic and proteomic investigations of impacts of titanium dioxide nanoparticles on Escherichia coli. [PDF]
PLoS ONE, 2017 In a previous study, it was demonstrated that the toxic impact of titanium dioxide nanoparticles on Escherichia coli starts at 10 ppm and is closely related to the presence of little aggregates.
Mariane Planchon +4 more
doaj +1 more source
Journal of Plant Interactions, 2020 In this study, two bread wheat (Triticum aestivum L.) cultivars, Pishgam (drought-tolerant) and Shahryar (drought-sensitive), were grown in the greenhouse under control and moisture stress conditions.
Maryam Nazari +3 more
doaj +1 more source