Prognostic Power of a Chaperonin Containing TCP-1 Subunit Genes Panel for Hepatocellular Carcinoma [PDF]
Frontiers in Genetics, 2021 Chaperonin containing TCP-1 (T-complex protein 1) (CCT) is a large molecular weight complex that contains nine subunits (TCP1, CCT2, CCT3, CCT4, CCT5, CCT6A, CCT6B, CCT7, CCT8). This study aimed to reveal key genes which encode CCT subunits for prognosis
Wenli Li, Jun Liu, Hetong Zhao
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The malaria parasite chaperonin containing TCP-1 (CCT) complex: Data integration with other CCT proteomes [PDF]
Frontiers in Molecular Biosciences, 2022 The multi-subunit chaperonin containing TCP-1 (CCT) is an essential molecular chaperone that functions in the folding of key cellular proteins. This paper reviews the interactome of the eukaryotic chaperonin CCT and its primary clients, the ubiquitous ...
Mark D. Wilkinson +5 more
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Polycomb Requires Chaperonin Containing TCP-1 Subunit 7 for Maintaining Gene Silencing in Drosophila [PDF]
Frontiers in Cell and Developmental Biology, 2021 In metazoans, heritable states of cell type-specific gene expression patterns linked with specialization of various cell types constitute transcriptional cellular memory.
Najma Shaheen +7 more
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Chaperonin containing TCP-1 (CCT/TRiC) is a novel therapeutic and diagnostic target for neuroblastoma [PDF]
Frontiers in Oncology, 2022 Chaperonin containing TCP1 (CCT/TRiC) is a multi-subunit protein folding complex that enables the cancer phenotype to emerge from the mutational landscape that drives oncogenesis.
Amanda Cox +8 more
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Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration [PDF]
Frontiers in Molecular NeuroscienceThe chaperonin TCP-1 ring complex (TRiC), also known as chaperonin-containing TCP-1 (CCT) complex, plays a crucial role in protein folding and quality control within the cell.
Vanlalrinchhani Varte +3 more
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Chaperonin‐containing TCP‐1 subunit 2‐mediated aggrephagy: A potential target for treating neurodegeneration [PDF]
Clinical and Translational Medicine, 2022 Xueshen Chen, Min Zhang
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Increased expression is a potential unfavourable factor promoting the growth of nasopharyngeal carcinoma [PDF]
Journal of International Medical ResearchObjective Chaperonin containing TCP1 subunit 5 ( CCT5 ) encodes the CCT5 protein subunit of chaperonin-containing TCP-1 (CCT/TRiC) complex, and is shown to be upregulated in tumour pathogenesis.
Shaoyu Wu, Lingrong Peng
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CCT7 Regulates TRAF6‐Mediated Autophagy to Promote Posttraumatic Joint Contracture [PDF]
J Cell Mol MedABSTRACT Posttraumatic joint contracture (PTJC) is a prevalent complication of joint injury, characterised by marked reductions in both active and passive joint motion. Previous studies have indicated that the chaperonin‐containing T‐complex polypeptide (CCT) is involved in fibrotic processes.
Li Y +7 more
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Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways [PDF]
Cancers, 2020 Yuan-Feng Lin +2 more
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Genetic expansion of chaperonin‐containing TCP‐1 (CCT/TRiC) complex subunits yields testis‐specific isoforms required for spermatogenesis in planarian flatworms [PDF]
Molecular Reproduction and Development, 2017 Labib Rouhana
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