Results 91 to 100 of about 4,735,203 (296)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Primary Homology Assessment, Characters and Character States

open access: yesCladistics, 1997
We discuss contrasting approaches to cladistic character definition and thus to cladistic data matrix compilation. The conventional approach considers character states as alternate forms of the “same thing” (the character). A review of the challenges to this convention is presented, and their implications evaluated.
Hawkins, J, Hughes, C, Scotland, R
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Role of Personalized Learning Program by Learning Management System in Higher Education in Binus Bandung Indonesia

open access: yesEngineering Proceedings
This study aims to provide an overview of the effectiveness and responsiveness of the personalized learning model in terms of Industry 4.0. A qualitative and descriptive research method was used as students, staff, and lecturers were interviewed.
Agus Masrukhin
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Modular Homology Characters [PDF]

open access: yesProceedings of the National Academy of Sciences, 1932
This paper gives definitions and some simple properties of homology characters modulo any integer preceded by a discussion of matrices modulo any integer.
openaire   +3 more sources

Involutions and the Gelfand character

open access: yes, 2018
The Gelfand representation of $\mathcal{S}_n$ is the multiplicity-free direct sum of the irreducible representations of $\mathcal{S}_n$. In this paper, we use a result of Adin, Postnikov, and Roichman to find a recursive generating function for the ...
Archer, Kassie   +3 more
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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