Results 111 to 120 of about 1,797,426 (298)

Character sheaves, IV

Advances in Mathematics, 1985
The author constructs a geometric theory of characters of a reductive algebraic group G defined over an algebraically closed field. This theory is as close as possible to the theory of irreducible (complex) characters of the corresponding group \(G(F_ q)\) over a finite field \(F_ q\) and yet it should have a meaning over an algebraically closed field.
openaire   +4 more sources

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Improving Walking Energy Efficiency in Transtibial Amputees Through the Integration of a Low-Power Actuator in an ESAR Foot

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Reducing energy consumption during walking is a critical goal for transtibial amputees. The study presents the evaluation of a semi-active prosthesis with five transtibial amputees.
Alessandro Mazzarini, Ilaria Fagioli, Huseyin Eken, Chiara Livolsi, Tommaso Ciapetti, Alessandro Maselli, Michele Piazzini, Claudio Macchi, Angelo Davalli, Emanuele Gruppioni, Emilio Trigili, Simona Crea, Nicola Vitiello   +12 more
doaj   +1 more source

The nature of natural: defining natural character for the New Zealand context [PDF]

, 2010
New Zealand has a long-standing statutory policy goal to preserve the natural character of the coastal environment and various freshwater environments and their margins. In the absence of an authoritative definition, it has not been possible to develop a
Bornman, Janet, Bornman, Janet F., Froude, Victoria A., Froude, V, Rennie, Hamish, Rennie, Hamish Gordon, Rennie, H., Bornman, J, Froude, V.   +8 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Youth moral development in a Chinese context: an empirical study of Self-Other Knowledge Asymmetry between self, parents, and teachers

Cogent Education
Moral education and fostering youth character development have become the foci of Chinese moral education; yet most existing studies are confined to the Chinese education community and not shared with an international audience.
Yan Huo, Cody Ding, Jin Xie, Jianlan Zhang, Francisco Moller, Kristján Kristjánsson   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source