Results 101 to 110 of about 4,735,203 (296)

Knowing the Words, Missing the Meaning: Evaluating LLMs’ Cultural Understanding Through Sino-Korean Words and Four-Character Idioms

Applied Sciences
This study proposes a new benchmark to evaluate the cultural understanding and natural language processing capabilities of large language models based on Sino-Korean words and four-character idioms.
Eunsong Lee, Hyein Do, Minsu Kim, Dongsuk Oh   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Pain Management Adequacy in Patients With Bone Metastases: A Secondary Analysis From the Palliative Radiotherapy and Inflammation Study Trial

Clinical Medicine Insights: Oncology
Background: Bone metastases (BMs) are a common complication in patients with cancer, often leading to significant pain that adversely affects quality of life, necessitating effective pain management strategies.
Savino Cilla, Romina Rossi, Costanza Maria Donati, Ragnhild Habberstad, Pal Klepstad, Monia Dall’Agata, Vanessa Valenti, Stein Kaasa, Federica Medici, Alessio Giuseppe Morganti, Marco Maltoni   +10 more
doaj   +1 more source

Honoring Roger Weissberg’s legacy by centering relationships, collaboration, and the wellbeing of all children through SEL

Social and Emotional Learning: Research, Practice, and Policy
We describe how the field of social and emotional learning (SEL) can best honor Roger Weissberg’s legacy from the perspective of an early collaborator, Maurice J.
Maurice J. Elias, Danielle R. Hatchimonji   +1 more
doaj   +1 more source

Parabolic character sheaves, III

, 2009
We define character sheaves on an ind-variety of the form G((t))/U_P where G((t)) is a loop group and U_P is the prounipotent radical of a parahoric subgroup P of G((t)).Comment: 8 ...
Lusztig, G.
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

SOCIAL MIMICRY; CHARACTER CONVERGENCE VERSUS CHARACTER DISPLACEMENT [PDF]

Evolution, 1968
In an earlier discussion of social behavior (Moynihan, 1960), it was suggested that there will usually be very strong selection pressure for or against the development, or maintenance, of similarities between any two species which come into contact with one another.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Improving Walking Energy Efficiency in Transtibial Amputees Through the Integration of a Low-Power Actuator in an ESAR Foot

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Reducing energy consumption during walking is a critical goal for transtibial amputees. The study presents the evaluation of a semi-active prosthesis with five transtibial amputees.
Alessandro Mazzarini, Ilaria Fagioli, Huseyin Eken, Chiara Livolsi, Tommaso Ciapetti, Alessandro Maselli, Michele Piazzini, Claudio Macchi, Angelo Davalli, Emanuele Gruppioni, Emilio Trigili, Simona Crea, Nicola Vitiello   +12 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source