Results 121 to 130 of about 6,238,972 (392)

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Online Learning with Digital Technology and Computer Software: New Experiences for Indonesian Students in Education Institutions

open access: yesEngineering Proceedings
The experiences of students in the online lectures of Binus University, Indonesia, were analyzed using a qualitative descriptive approach. Offline and online interviews were conducted for data collection.
Agus Masrukhin
doaj   +1 more source

Parabolic character sheaves, III

open access: yes, 2009
We define character sheaves on an ind-variety of the form G((t))/U_P where G((t)) is a loop group and U_P is the prounipotent radical of a parahoric subgroup P of G((t)).Comment: 8 ...
Lusztig, G.
core  

Character Sequence Models for ColorfulWords

open access: yes, 2016
We present a neural network architecture to predict a point in color space from the sequence of characters in the color's name. Using large scale color--name pairs obtained from an online color design forum, we evaluate our model on a "color Turing test"
Dyer, Chris   +3 more
core   +1 more source

Char-Net: A Character-Aware Neural Network for Distorted Scene Text Recognition

open access: yesAAAI Conference on Artificial Intelligence, 2018
In this paper, we present a Character-Aware Neural Network (Char-Net) for recognizing distorted scene text. Our Char-Net is composed of a word-level encoder, a character-level encoder, and a LSTM-based decoder.
W. Liu   +2 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Truncated convolution of character sheaves [PDF]

open access: yes, 2014
Let G be a reductive connected group over an algebraic closure of a finite field. I define a tensor structure on the category of perverse sheaves on G which are direct sums of unipotent character sheaves in a fixed two-sided cell, in accordance with a ...
Lusztig, G.
core  

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

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