Results 61 to 70 of about 536,114 (266)
Characteristic energy factors for energy sink problem of the ideal fluid cavity annihilation
Baozha yu ChongjiIn physics, a “source” denotes the origin of matter or energy, while a “sink” refers to the terminal point of matter or energy. By analogizing with the energy source problem in underground explosions, this study proposes an energy sink problem for ideal ...
Haoxiang CHEN +3 more
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Frontiers in Psychology, 2015 Mental arithmetic is a powerful paradigm to study problem solving using neuroimaging methods. However, the evaluation of task complexity varies significantly across neuroimaging studies.
Nadja eTschentscher, Olaf eHauk
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FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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On the solvability of the Sturm – Liouville problem, nonlinear in the spectral parameter
Известия высших учебных заведений. Поволжский регион: Физико-математические наукиBackground. The paper studies the solvability of the Sturm-Liouville problem, which is nonlinear in the spectral parameter. The problem is studied on a segment with boundary conditions of the third kind. Materials and methods.
G.V. Chalyshov
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Oscillatory solutions of the Cauchy problem for linear differential equations
Electronic Journal of Differential Equations, 2015 We consider the Cauchy problem for second and third order linear differential equations with constant complex coefficients. We describe necessary and sufficient conditions on the data for the existence of oscillatory solutions. It is known that in the
Gro Hovhannisyan, Oliver Ruff
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
A study on one algebraic equation of the product equaling unit
四川大学学报. 自然科学版, 2016 In this paper, we consider the relationship between the Deligne-Simpson problem and the Hurwitz enumeration problem. First, we observe that they are the solutions of the same algebraic equation on different groups, which the algebraic equation is (A_1 ...
LI Sha-Sha, ZHENG Quan
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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