Results 51 to 60 of about 7,153,426 (306)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
On Riemann method for solving a mixed problem
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2007 The formula for solution of a problem for an equation with the higher partial derivative of the general type is constructed using Riemann method. In this problem the solution is found in the characteristic parallelepiped with separated by the non ...
A. N. Mironov
doaj +1 more source
Occurrences of palindromes in characteristic Sturmian words [PDF]
, 2006 This paper is concerned with palindromes occurring in characteristic Sturmian words cα of slope α, where α∈(0,1) is an irrational. As cα is a uniformly recurrent infinite word, any (palindromic) factor of cα occurs infinitely many times in cα with ...
Glen, Amy, Glen, Amy Louise, Glen, A.
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
ONE-SIDED \(L\)-APPROXIMATION ON A SPHERE OF THE CHARACTERISTIC FUNCTION OF A LAYER
Ural Mathematical Journal, 2018 In the space \(L(\mathbb{S}^{m-1})\) of functions integrable on the unit sphere \(\mathbb{S}^{m-1}\) of the Euclidean space \(\mathbb{R}^{m}\) of dimension \(m\ge 3\), we discuss the problem of one-sided approximation to the characteristic function of a ...
Marina V. Deikalova +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A similar for ∆1 problem for the second order hyperbolic equation in the 3D euclidean space
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2015 The second-order hyperbolic type equation is considered in the 3D Euclidean space. Boundary value problem is posed in the infinite cylindrical region bounded by the characteristic surfaces of this equation with data on the related characteristic surfaces ...
Irina N Rodionova +1 more
doaj +1 more source
Karakteristik Seni Kerajinan Eceng Gondok Gorontalo
Dewa Ruci: Jurnal Pengkajian dan Penciptaan Seni, 2020 Upaya pengembangan kerajinan eceng gondok di Gorontalo sebagai sektor unggulan harus dilandasi oleh karakteristik yang meliputi potensi dan permasalahan. Namun, data tentang karakteristik kerajinan belum tersedia secara komprehensif.
I Wayan - Sudana, Isnawati Mohamad
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Paradigmatic well posedness in some generalized characteristic Cauchy problems [PDF]
By means of convenient regularization for an ill posed Cauchy problem, we deï¬ne an associated generalized problem and discuss the conditions for the solvability of it.
Emmanuel Allaud +4 more
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