Results 81 to 90 of about 40,876 (272)

A Lower Bound for Continuous Convex Mappings on Normed Linear Spaces

open access: yes, 1998
A lower bound for continuous convex mappings defined on normed linear spaces in terms of norm derivatives and best approximants is ...
Dragomir, Sever S
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

CHARACTERIZATIONS AND UNIQUENESS OF BEST SIMULTANEOUS $\tau_C$-APPROXIMATIONS

open access: yesTaiwanese Journal of Mathematics, 2011
This paper is concerned with the problem of best simultaneous $\tau_C$-approximations in terms of the Minkowski functional. The notions of simultaneous sun and simultaneous regular set are extended to suit the case of simultaneous $\tau_C$-approximation problems. Characterization and uniqueness results are established for simultaneous $\tau_C$-suns.
Luo, X. F.   +3 more
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Empirical Rules for Oscillation and Harmonic Approximation of Fractional Kelvin–Voigt Oscillators

open access: yesApplied Sciences
Fractional Kelvin–Voigt (FKV) oscillators describe vibrations in viscoelastic structures with memory effects, leading to dynamics that are often more complex than those of classical harmonic oscillators.
Paweł Łabędzki
doaj   +1 more source

Fixed points and best approximation in Menger convex metric spaces [PDF]

open access: yes, 2005
summary:We obtain necessary conditions for the existence of fixed point and approximate fixed point of nonexpansive and quasi nonexpansive maps defined on a compact convex subset of a uniformly convex complete metric space.
Beg, Ismat, Abbas, Mujahid
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Generalised Fictitious Play for a Continuum of Anonymous Players

open access: yes, 2009
Recently, efficient approximation algorithms for finding Nash equilibria have been developed for the interesting class of anonymous games, where a player's utility does not depend on the identity of its opponents.
Rabinovich, Zinovi   +4 more
core  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

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