Results 61 to 70 of about 357,643 (260)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Characterization of \(\varepsilon\)-nearest points in spaces with asymmetric seminorm

Journal of Numerical Analysis and Approximation Theory, 2004
In this note we are concerned with the characterization of the elements of \(\varepsilon\)-best approximation (\(\varepsilon\)-nearest points) in a subspace \(Y\) of space \(X\) with asymmetric seminorm. For this we use functionals in the asymmetric dual
Costică Mustăţa
doaj   +2 more sources

Birkhoff-James orthogonality and applications : A survey

, 2020
In the last few decades, the concept of Birkhoff-James orthogonality has been used in several applications. In this survey article, the results known on the necessary and sufficient conditions for Birkhoff-James orthogonality in certain Banach spaces are
Grover, Priyanka, Sushil
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Characterization of best approximations by sums of exponentials

Journal of Approximation Theory, 1973
AbstractAn exponential sum y can be specified by giving the coefficients b, c of the corresponding initial value problem (Dn + c1Dn − 1 + ··· + cn)y = 0, Dj − 1y(0) = bj, j = 1, 2,…, n. We discuss some of the topological properties of this parametric form, noting that the associated tangential manifold does not suffer a “loss of dimension” when the ...
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Characterization of best algebraic approximation by a generalized modulus of smoothness [PDF]

AIP Conference Proceedings, 2019
The paper presents Jackson inequality and the corresponding inverse inequality for the best algebraic approximation in terms of the generalized moduli of smoothness. Moreover the equivalence between the generalized modulus and the Butzer-Stens modulus is shown.
Teodora Zapryanova, Diko Souroujon
openaire   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Characterization of the best integral approximant of multivariable functions

Researches in Mathematics, 2021
We obtain the criterion of the best approximant for multivariable functions in $L_{p_1,\ldots p_n}$ space.
openaire   +2 more sources