Results 101 to 110 of about 12,815 (205)

Sound offset responses become highly informative in the auditory cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Using large datasets of neural responses to diverse sounds recorded across four stages of the mouse auditory system (depicted and colour‐coded on the left), offset responses occurring after the termination of each sound (time window indicated by the orange shaded area superimposed with activity traces) were characterized and it ...
Charly Lamothe   +3 more
wiley   +1 more source

Engineering of 2‐ketoacid Decarboxylases for Production of Isobutanol and Other Fusel Alcohols in Saccharomyces cerevisiae

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 4, Page 1036-1049, April 2026.
ABSTRACT Isobutanol is a fusel alcohol that can be produced microbially for use as a biofuel or upgraded into sustainable aviation fuel (SAF). A key enzyme in the isobutanol biosynthetic pathway is 2‐ketoacid decarboxylase (KDC), which irreversibly decarboxylates 2‐ketoisovalerate (KIV) to yield isobutyraldehyde.
Joshua J. Dietrich   +6 more
wiley   +1 more source

Tn‐seq of Thermus thermophilus Genome Reveals Unexpected Tolerance to Insertions in Bacterial Common Essential Genes

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Tn‐seq analysis of Thermus thermophilus genome reveals insertions in almost all genes, this is, there is no clear discrimination of essential genes. A similar result has not been reported in other Tn‐seq analysis of bacterial genomes so far. The polyploidy of the Thermus genome could explain the apparent non‐essentiality of key genes.
Cristina L. Gómez‐Campo   +6 more
wiley   +1 more source

Dynamic Lysine Acetylation Disrupts Isocitrate Lyase Function and Enables Metabolic Optimisation

open access: yesMicrobial Biotechnology, Volume 19, Issue 4, April 2026.
Acetyl‐phosphate–dependent acetylation of E. coli isocitrate lyase (ICL) at K13 and K308 inhibits its activity, while CobB‐mediated deacetylation restores function. Introducing K13R/K308R mutations enhances metabolic balance and increases lycopene yield by 61%, providing a promising approach to optimise microbial cell factories through natural ...
Adrián Martínez‐Vivancos   +6 more
wiley   +1 more source

A FIRST APPROXIMATION CALCULATION OF AIR CUSHION CHASSIS WEIGHT OF TRANSPORT AIRPLANE

open access: yesНаучный вестник МГТУ ГА, 2016
This article describes a first approximation of a weighted estimate of air cushion chassis. The algorithm for calculating the weight of air cushion chassis allows not only to estimate the mass of the chassis to a first approximation, but also to conduct ...
V. P. Morozov, Y. Y. Merzlikin
doaj  

Engineering Yeast Extracellular Vesicle Biogenesis Through Rewiring Membrane Trafficking Pathways

open access: yesMicrobial Biotechnology, Volume 19, Issue 4, April 2026.
Engineered Saccharomyces cerevisiae reveals how cell wall remodelling and membrane trafficking coordinate extracellular vesicle biogenesis. Interferon overexpression and chs3 deletion enhance EV secretion and reshape SNARE‐, Rab‐ and ESCRT‐associated pathways, establishing yeast as a versatile platform for EV engineering and therapeutic cargo loading ...
Yueyan Li   +11 more
wiley   +1 more source

A flexible automated magnetic microrobot assembly system. [PDF]

open access: yesJ Microbio Robot
Shindell OJ, Davis AC, Cappelleri DJ.
europepmc   +1 more source

Engineering of the Flavone Rutinoside Biosynthetic Pathway Enables Production of Diosmin, a Venoactive Compound in Solanum lycopersicum and Nicotiana tabacum

open access: yesPlant Biotechnology Journal, Volume 24, Issue 4, Page 1936-1949, April 2026.
ABSTRACT Diosmin is often used as a dietary supplement, and it is sometimes used to make phlebotropic drugs for venous diseases. Traditionally, diosmin is obtained by the dehydrogenation of the flavanone glycoside hesperidin through chemical semisynthesis.
Qianle Zhang   +5 more
wiley   +1 more source

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