Results 51 to 60 of about 100,948 (293)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Stereotypes in ChatGPT - an empirical study [PDF]

open access: yes, 2023
ChatGPT is rapidly gaining interest and attracts many researchers, practitioners and users due to its availability, potentials and capabilities.
Bargh, M.S., Busker, A.L.J., Choenni, S.
core  

"Natürlich! Hier ist die Übersetzung des Abschnitts in Deutsch:

open access: yes, 2023
ChatGPT Deutsch - Eine automatisierte Kundenunterstützungslösung In der digitalen Ära ist das Geschäftsumfeld zunehmend komplex und wettbewerbsintensiv geworden.
ChatGPT Deustch
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

The language of ChatGPT [PDF]

open access: yes
 Miscin, E. (2024). The Language of ChatGPT. In D. K.-G. Chan et al. (Eds.), Evolving trends in foreign language education: Past lessons, present reflections, future directions. Proceedings from the 10th CLaSIC 2024 (pp. 249–258). Centre for Language Studies, Faculty of Arts and Social Sciences, National University of Singapore. https://doi.org/10.5281/
openaire   +2 more sources

ChatGPT-4 answers to JAMA Ophthalmology Clinical Challenges

open access: yes, 2023
This is a list of ChatGPT-4's answers to the 'What Would You Do Next' question (column C) as well as if the model correctly determined the diagnosis on the first attempt (column D).
ANTONIO YAGHY (17081968)
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

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