Results 71 to 80 of about 122,373 (292)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Is It Getting Better? An Evaluation of Two Successive Generations of ChatGPT in Answering Specialized Vascular Surgery Questions

open access: yesVascular Specialist International
Purpose: Large language models (LLMs) can generate clinically relevant text; however, their performance in highly specialized medical domains remains uncertain.
Dongjin Suh   +4 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Exploring the Usage of ChatGPT Among Medical Students in the United States

open access: yesJournal of Medical Education and Curricular Development
OBJECTIVES Chat Generative Pretrained Transformer (ChatGPT) is a large language model developed by OpenAI that has gained widespread interest. It has been cited for its potential impact on health care and its beneficial role in medical education. However,
Janice S. Zhang   +3 more
doaj   +1 more source

ChatGPT sur ChatGPT

open access: yesÉpistemologie de la psychologie
Utiliser un tel système, c’est interagir avec un rituel de production de crédibilité. Le risque n’est pas qu’il dise quelque chose de faux, mais qu’il génère de la croyance sans opérateur de vérité identifiable.Il faut le considérer non comme un sujet pensant, ni même comme un outil,mais comme une machine à induire de l’adhésion fluide — ce qui le rend
openaire   +1 more source

Taking Advice from ChatGPT

open access: yes, 2023
A growing literature studies how humans incorporate advice from algorithms. This study examines an algorithm with millions of daily users: ChatGPT. We conduct a lab experiment in which 118 student participants answer 2,828 multiple-choice questions ...
Peter Zhang
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

ChatGPT-3,5 and ChatGPT-4o performance in Specialty Certificate Examination in Diabetology: a comparative study.

open access: yesClinical Diabetology
OBJECTIVE: ChatGPT is an AI-powered chatbot that nowadays is becoming a valuable tool in various medical fields. In this study, we compare the effectiveness of ChatGPT-3.5 and ChatGPT-4o in completing the Specialty Certificate Examination in Diabetology.
Katarzyna Kler   +5 more
doaj   +1 more source

ChatGPT-4 answers to JAMA Ophthalmology Clinical Challenges

open access: yes, 2023
This is a list of ChatGPT-4's answers to the 'What Would You Do Next' question (column C) as well as if the model correctly determined the diagnosis on the first attempt (column D).
ANTONIO YAGHY (17081968)
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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