Results 61 to 70 of about 131,637 (287)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

ChatGPT for computational topology

open access: yesFoundations of Data Science
ChatGPT represents a significant milestone in the field of artificial intelligence (AI), finding widespread applications across diverse domains. However, its effectiveness in mathematical contexts has been somewhat constrained by its susceptibility to conceptual errors.
Jian Liu, Li Shen, Guo-Wei Wei 0001
openaire   +4 more sources

Everything You Wanted To Know About Chatgpt: Components, Capabilities, Applications, and Opportunities

open access: yes
Heidari, Arash/0000-0003-4279-8551Conversational Artificial Intelligence (AI) and Natural Language Processing have advanced significantly with the creation of a Generative Pre-trained Transformer (ChatGPT) by OpenAI. ChatGPT uses deep learning techniques
Navimipour, Nima Jafari   +4 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

ChatGPT in psychiatry: promises and pitfalls

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery
ChatGPT has become a hot topic of discussion since its release in November 2022. The number of publications on the potential applications of ChatGPT in various fields is on the rise.
Rebecca Shin-Yee Wong
doaj   +1 more source

Insights into nurse educators' use of ChatGPT in active teaching methods: A cross-sectional pilot study

open access: yesEducación Médica
Introduction: Artificial intelligence has revolutionized nursing education with the emergence of ChatGPT, which has the potential to transform active teaching methods.
Asma Bouriami   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The language of ChatGPT [PDF]

open access: yes
 Miscin, E. (2024). The Language of ChatGPT. In D. K.-G. Chan et al. (Eds.), Evolving trends in foreign language education: Past lessons, present reflections, future directions. Proceedings from the 10th CLaSIC 2024 (pp. 249–258). Centre for Language Studies, Faculty of Arts and Social Sciences, National University of Singapore. https://doi.org/10.5281/
openaire   +2 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy