Results 41 to 50 of about 13,565 (267)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
PRINSIP CHECKS AND BALANCES DITINJAU DARI SISI DAN PRAKTIK
The purpose of this research is to get a full description about the parliament concept in Indonesia that no clear enough use Threecameralism system (MPR, DPR, DPD) Bicameralism (DPR and DPD), or Unycameralism (MPR).
FAHARUDIN FAHARUDIN
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Checks and balances in weakly institutionalized countries
Tesis (Magíster en Economía)--Pontificia Universidad Católica de Chile, 2014We extend a model by Acemoglu et al (2013) developed to explain this phenomenon, and include a measure of natural resource wealth in the government budget constraint.
Baragwanath Vogel, Kathryn
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Charter Checks and Parliamentary Balances
According to its most enthusiastic support- ers, the Canadian Charter of Rights and Free- doms1 fulfills two major functions in Canada’s democratic regime: 1) it shields minorities from the excesses of majoritarian decision-making, in effect guarding ...
Baker Dennis +3 more
core +1 more source
Can political gridlock undermine checks and balances? A lab experiment [PDF]
If checks and balances are aimed at protecting citizens from the government’s abuse of power, why do they sometimes weaken them? We address this question in a laboratory experiment in which subjects choose between two decision rules: with and without ...
Forteza, A., Mussio, I., Pereyra, J.S.
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
IMPLIKASI PUTUSAN MAHKAHAM KONSTITUSI SEBAGAI POSITIF LEGISLATOR TERHADAP PRINSIP CHECK AND BALANCE
Penelitian ini mengkaji implikasi putusan Mahkamah Konstitusi yang bersifat positif legislator terhadap prinsip checks and balances dalam sistem ketatanegaraan Indonesia.
Dewi Sulastri, Abu Sanmas
doaj +1 more source

